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Joseph M Josephides

Explore the profile of Joseph M Josephides including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Josephides J, Chen C
Nat Commun . 2025 Feb; 16(1):1472. PMID: 39922809
Genomic heterogeneity has largely been overlooked in single-cell replication timing (scRT) studies. Here, we develop MnM, an efficient machine learning-based tool that allows disentangling scRT profiles from heterogenous samples. We...
2.
Gnan S, Josephides J, Wu X, Spagnuolo M, Saulebekova D, Bohec M, et al.
Nat Commun . 2022 Apr; 13(1):2329. PMID: 35484127
Mammalian genomes are replicated in a cell type-specific order and in coordination with transcription and chromatin organization. Currently, single-cell replication studies require individual processing of sorted cells, yielding a limited...