Joseph M Dhahbi
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Explore the profile of Joseph M Dhahbi including associated specialties, affiliations and a list of published articles.
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32
Citations
1177
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Recent Articles
1.
Cano-Besquet S, Park M, Berkley N, Wong M, Ashiqueali S, Noureddine S, et al.
Geroscience
. 2024 Oct;
PMID: 39405012
Our study investigates gene expression in adipose tissue of Ames dwarf (df/df) mice, whose deficiency in growth hormone is linked to health and extended lifespan. Recognizing adipose tissue influence on...
2.
Saccon T, Dhahbi J, Schneider A, Nunez Lopez Y, Qasem A, Cavalcante M, et al.
Biology (Basel)
. 2022 Apr;
11(4).
PMID: 35453708
Crohn's disease (CD) and rheumatoid arthritis (RA) are immune mediated inflammatory diseases. Several studies indicate a role for microRNAs (miRNAs) in the pathogenesis of a variety of autoimmune diseases, including...
3.
Dhahbi J, Chen J, Bhupathy S, Atamna H, Cavalcante M, Saccon T, et al.
J Gerontol A Biol Sci Med Sci
. 2021 Aug;
76(9):1561-1570.
PMID: 34387333
The Ames dwarf (df/df) mouse is a well-established model for delayed aging. MicroRNAs (miRNAs), the most studied small noncoding RNAs (sncRNAs), may regulate ovarian aging to maintain a younger ovarian...
4.
Dhahbi J, Atamna H, Selth L
Biomark Cancer
. 2018 Mar;
10:1179299X18759545.
PMID: 29497340
Extracellular RNAs are gaining clinical interest as biofluid-based noninvasive markers for diseases, especially cancer. In particular, derivatives of transfer RNA (tRNA) are emerging as a new class of small-noncoding RNAs...
5.
Atamna H, Tenore A, Lui F, Dhahbi J
Biogerontology
. 2018 Jan;
19(2):171-184.
PMID: 29335816
"Organ reserve" refers to the ability of an organ to successfully return to its original physiological state following repeated episodes of stress. Clinical evidence shows that organ reserve correlates with...
6.
Schneider A, Dhahbi J, Atamna H, Clark J, Colman R, Anderson R
Aging Cell
. 2017 Jul;
16(5):1200-1203.
PMID: 28677323
Caloric restriction (CR) is one of the most robust interventions shown to delay aging in diverse species, including rhesus monkeys (Macaca mulatta). Identification of factors involved in CR brings a...
7.
Dhahbi J, Atamna H, Li R, Yamakawa A, Guerrero N, Lam H, et al.
Genomics Insights
. 2016 Apr;
9:29-39.
PMID: 27042094
In mammals, extracellular miRNAs circulate in biofluids as stable entities that are secreted by normal and diseased tissues, and can enter cells and regulate gene expression. Drosophila melanogaster is a...
8.
Atamna H, Atamna W, Al-Eyd G, Shanower G, Dhahbi J
Redox Biol
. 2015 Sep;
6:426-435.
PMID: 26386875
Methylene blue (MB) delays cellular senescence, induces complex-IV, and activates Keap1/Nrf2; however, the molecular link of these effects to MB is unclear. Since MB is redox-active, we investigated its effect...
9.
Vuong L, Chellappa K, Dhahbi J, Deans J, Fang B, Bolotin E, et al.
Mol Cell Biol
. 2015 Aug;
35(20):3471-90.
PMID: 26240283
The nuclear receptor hepatocyte nuclear factor 4α (HNF4α) is tumor suppressive in the liver but amplified in colon cancer, suggesting that it also might be oncogenic. To investigate whether this...
10.
Victoria B, Dhahbi J, Nunez Lopez Y, Spinel L, Atamna H, Spindler S, et al.
Aging Cell
. 2015 Jul;
14(6):1055-66.
PMID: 26176567
Recent evidence demonstrates that serum levels of specific miRNAs significantly change with age. The ability of circulating sncRNAs to act as signaling molecules and regulate a broad spectrum of cellular...