Joseph Kost
Overview
Explore the profile of Joseph Kost including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
655
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0
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Recent Articles
1.
Buaron N, Mangraviti A, Wang Y, Liu A, Pedone M, Sankey E, et al.
Bioeng Transl Med
. 2024 Nov;
9(5):e10660.
PMID: 39553432
Glioma is one of the most common primary malignant brain tumors. Despite progress in therapeutic approaches, the median survival of patients with glioma remains less than 2 years, generating the...
2.
Amar-Lewis E, Cohen L, Chintakunta R, Benafsha C, Lavi Y, Goldbart R, et al.
Small
. 2024 Oct;
20(51):e2405524.
PMID: 39359045
Starch-based nanoparticles are highly utilized in the realm of drug delivery taking advantage of their biocompatibility and biodegradability. Studies have utilized Quaternized starch (Q-starch) for small interfering RNA (siRNA) delivery,...
3.
Blitsman Y, Hollander E, Benafsha C, Yegodayev K, Hadad U, Goldbart R, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38339058
Given the role of phosphatidylinositol 3,4,5-trisphosphate (PIP3) in modulating cellular processes such as proliferation, survival, and migration, we hypothesized its potential as a novel therapeutic agent for wound closure enhancement....
4.
Blitsman Y, Benafsha C, Yarza N, Zorea J, Goldbart R, Traitel T, et al.
Nanomaterials (Basel)
. 2023 Jul;
13(13).
PMID: 37446506
The tailored design of drug delivery systems for specific therapeutic agents is a prevailing approach in the field. In this paper, we present a study that highlights the potential of...
5.
Schnaider L, Shimonov L, Kreiser T, Zaguri D, Bychenko D, Brickner I, et al.
ACS Appl Bio Mater
. 2022 Jan;
3(12):8395-8401.
PMID: 35019611
The skin is a key site for drug administration because of its large surface area and noninvasive accessibility. However, the dermal architecture serves as an excellent barrier, protecting from external...
6.
Bergman E, Goldbart R, Traitel T, Amar-Lewis E, Zorea J, Yegodayev K, et al.
Bioeng Transl Med
. 2021 Sep;
6(3):e10226.
PMID: 34589601
We hypothesize that the biomechanical properties of cells can predict their viability, with Young's modulus representing the former and cell sensitivity to ultrasound representing the latter. Using atomic force microscopy,...
7.
Tsirkin S, Goldbart R, Traitel T, Kost J
ACS Appl Mater Interfaces
. 2021 May;
13(22):25748-25758.
PMID: 34048218
Microbubbles (MBs), being gas bubbles encapsulated inside a solid shell, have been investigated extensively in the field of therapeutic ultrasound as acoustic cavitation enhancers. Hard-shell MBs have an advantage over...
8.
Cohen S, Kingma P, Whitsett J, Goldbart R, Traitel T, Kost J
Int J Pharm
. 2020 May;
585:119387.
PMID: 32473376
Preterm infants, particularly those who born between 23 and 28 weeks' gestation, suffer from a very high incidence of respiratory distress syndrome (RDS) related to pulmonary immaturity and inability to...
9.
Lifshiz Zimon R, Lerman G, Elharrar E, Meningher T, Barzilai A, Masalha M, et al.
J Control Release
. 2018 Jun;
284:103-111.
PMID: 29870766
Psoriasis is a common, worldwide autoinflammatory, incurable skin disease. miR-197 has therapeutic potential for psoriasis since it can down-regulate the expression of both IL-22RA1 and IL-17RA, subunits of the receptors...
10.
Azagury A, Amar-Lewis E, Appel R, Hallak M, Kost J
Eur J Pharm Biopharm
. 2017 May;
117:292-299.
PMID: 28465240
Chemical penetration enhancers (CPEs) have long been used for mass transport enhancement across membranes. Many CPEs are used in a solution or gel and could be a solvent. The use...