Joseph J Hale
Overview
Explore the profile of Joseph J Hale including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
253
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0
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Recent Articles
1.
Hale J, Matsui T, Goldstein I, Mullis M, Roy K, Ville C, et al.
Nat Commun
. 2024 May;
15(1):4234.
PMID: 38762544
Interactions between genetic perturbations and segregating loci can cause perturbations to show different phenotypic effects across genetically distinct individuals. To study these interactions on a genome scale in many individuals,...
2.
Hale J, Matsui T, Goldstein I, Mullis M, Roy K, Ville C, et al.
bioRxiv
. 2024 Jan;
PMID: 38293072
Interactions between genetic perturbations and segregating loci can cause perturbations to show different phenotypic effects across genetically distinct individuals. To study these interactions on a genome scale in many individuals,...
3.
Matsui T, Mullis M, Roy K, Hale J, Schell R, Levy S, et al.
Nat Commun
. 2022 Mar;
13(1):1463.
PMID: 35304450
In diploid species, genetic loci can show additive, dominance, and epistatic effects. To characterize the contributions of these different types of genetic effects to heritable traits, we use a double...
4.
Schell R, Hale J, Mullis M, Matsui T, Foree R, Ehrenreich I
Genetics
. 2022 Jan;
220(3).
PMID: 35078232
Genetic background often influences the phenotypic consequences of mutations, resulting in variable expressivity. How standing genetic variants collectively cause this phenomenon is not fully understood. Here, we comprehensively identify loci...
5.
Milligan J, Lee D, Jackson D, Schaub A, Beld J, Barajas J, et al.
Nat Chem Biol
. 2019 Jun;
15(7):669-671.
PMID: 31209348
Fatty acid synthases are dynamic ensembles of enzymes that can biosynthesize long hydrocarbon chains efficiently. Here we visualize the interaction between the Escherichia coli acyl carrier protein (AcpP) and β-ketoacyl-ACP-synthase...
6.
Bazazi S, Bartumeus F, Hale J, Couzin I
PLoS Comput Biol
. 2012 May;
8(5):e1002498.
PMID: 22589707
Animals can exhibit complex movement patterns that may be the result of interactions with their environment or may be directly the mechanism by which their behaviour is governed. In order...
7.
Gallup A, Hale J, Sumpter D, Garnier S, Kacelnik A, Krebs J, et al.
Proc Natl Acad Sci U S A
. 2012 Apr;
109(19):7245-50.
PMID: 22529369
Pedestrian crowds can form the substrate of important socially contagious behaviors, including propagation of visual attention, violence, opinions, and emotional state. However, relating individual to collective behavior is often difficult,...
8.
Bazazi S, Romanczuk P, Thomas S, Schimansky-Geier L, Hale J, Miller G, et al.
Proc Biol Sci
. 2010 Aug;
278(1704):356-63.
PMID: 20739320
In order to move effectively in unpredictable or heterogeneous environments animals must make appropriate decisions in response to internal and external cues. Identifying the link between these components remains a...
9.
Bazazi S, Buhl C, Hale J, Anstey M, Sword G, Simpson S, et al.
Curr Biol
. 2008 May;
18(10):735-739.
PMID: 18472424
Plagues of mass migrating insects such as locusts are estimated to affect the livelihood of one in ten people on the planet [1]. Identification of generalities in the mechanisms underlying...