Joseph C Watkins
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Explore the profile of Joseph C Watkins including associated specialties, affiliations and a list of published articles.
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34
Citations
570
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Recent Articles
1.
Hack J, Watkins J, Schreiber J, Hammer M
Epilepsia
. 2024 Nov;
65(11):3324-3334.
PMID: 39556335
Objective: Phenotypic heterogeneity presents challenges in providing clinical care to patients with pathogenic SCN8A variants, which underly a wide disease spectrum ranging from neurodevelopmental delays without seizures to a continuum...
2.
Sun S, Hara A, Johnstone L, Hallmark B, Watkins J, Thomson C, et al.
Nutrients
. 2024 Sep;
16(17).
PMID: 39275249
Conflicting clinical trial results on omega-3 highly unsaturated fatty acids (n-3 HUFA) have prompted uncertainty about their cardioprotective effects. While the VITAL trial found no overall cardiovascular benefit from n-3...
3.
Hammer M, Bahramnejad E, Watkins J, Ronaldson P
Clin Sci (Lond)
. 2024 Aug;
138(17):1089-1110.
PMID: 39092536
Blockade of Angiotensin type 1 receptor (AT1R) has potential therapeutic utility in the treatment of numerous detrimental consequences of epileptogenesis, including oxidative stress, neuroinflammation, and blood-brain barrier (BBB) dysfunction. We...
4.
Hara A, Lu E, Johnstone L, Wei M, Sun S, Hallmark B, et al.
Bioinform Biol Insights
. 2024 Jul;
18:11779322241261427.
PMID: 39081667
The secreted phospholipase A (sPLA) isoform, sPLA-IIA, has been implicated in a variety of diseases and conditions, including bacteremia, cardiovascular disease, COVID-19, sepsis, adult respiratory distress syndrome, and certain cancers....
5.
Lu E, Hara A, Sun S, Hallmark B, Snider J, Seeds M, et al.
Eur J Immunol
. 2024 Apr;
54(6):e2350721.
PMID: 38651231
Previous research suggests that group IIA-secreted phospholipase A (sPLA-IIA) plays a role in and predicts lethal COVID-19 disease. The current study reanalyzed a longitudinal proteomic data set to determine the...
6.
Hack J, Watkins J, Hammer M
Biol Open
. 2024 Mar;
13(4).
PMID: 38466077
Distinguishing clinical subgroups for patients suffering with diseases characterized by a wide phenotypic spectrum is essential for developing precision therapies. Patients with gain-of-function (GOF) variants in the SCN8A gene exhibit...
7.
Hammer M, Krzyzaniak C, Bahramnejad E, Smelser K, Hack J, Watkins J, et al.
Clin Sci (Lond)
. 2024 Feb;
138(4):205-223.
PMID: 38348743
Background: Epilepsy is a common neurological disease; however, few if any of the currently marketed antiseizure medications prevent or cure epilepsy. Discovery of pathological processes in the early stages of...
8.
Hara A, Lu E, Johnstone L, Wei M, Sun S, Hallmark B, et al.
bioRxiv
. 2024 Jan;
PMID: 38168258
The secreted phospholipase A (sPLA ) isoform, sPLA -IIA, has been implicated in a variety of diseases and conditions, including bacteremia, cardiovascular disease, COVID-19, sepsis, adult respiratory distress syndrome, and...
9.
Bahramnejad E, Barney E, Lester S, Hurtado A, Thompson T, Watkins J, et al.
Int J Neurosci
. 2023 Nov;
134(12):1611-1623.
PMID: 37929583
Aims: Females and males of all ages are affected by epilepsy; however, unlike many clinical studies, most preclinical research has focused on males. Genetic variants in the voltage-gated sodium channel...
10.
Andrews J, Galindo M, Hack J, Watkins J, Conecker G, Hammer M
J Registry Manag
. 2023 Aug;
50(1):4-10.
PMID: 37577282
Genetic variants in the gene underlie a wide spectrum of neurodevelopmental phenotypes that range from severe epileptic encephalopathy to benign familial infantile epilepsy to neurodevelopmental delays with or without seizures....