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Fernando L Mendez

Explore the profile of Fernando L Mendez including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 1482
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Recent Articles
1.
Li X, Liu T, Bacchiocchi A, Li M, Cheng W, Wittkop T, et al.
EMBO Mol Med . 2024 Aug; 16(9):2188-2209. PMID: 39164471
While whole genome sequencing (WGS) of cell-free DNA (cfDNA) holds enormous promise for detection of molecular residual disease (MRD), its performance is limited by WGS error rate. Here we introduce...
2.
Fregel R, Mendez F, Bokbot Y, Martin-Socas D, Camalich-Massieu M, Santana J, et al.
Proc Natl Acad Sci U S A . 2018 Jun; 115(26):6774-6779. PMID: 29895688
The extent to which prehistoric migrations of farmers influenced the genetic pool of western North Africans remains unclear. Archaeological evidence suggests that the Neolithization process may have happened through the...
3.
Mendez F
Theor Popul Biol . 2016 Dec; 114:19-28. PMID: 27915040
Difference in male and female effective population sizes has, at times, been attributed to both sexes having unequal variance in their number of offspring. Such difference is paralleled by the...
4.
Poznik G, Xue Y, Mendez F, Willems T, Massaia A, Wilson Sayres M, et al.
Nat Genet . 2016 Apr; 48(6):593-9. PMID: 27111036
We report the sequences of 1,244 human Y chromosomes randomly ascertained from 26 worldwide populations by the 1000 Genomes Project. We discovered more than 65,000 variants, including single-nucleotide variants, multiple-nucleotide...
5.
Mendez F, Poznik G, Castellano S, Bustamante C
Am J Hum Genet . 2016 Apr; 98(4):728-34. PMID: 27058445
Sequencing the genomes of extinct hominids has reshaped our understanding of modern human origins. Here, we analyze ∼120 kb of exome-captured Y-chromosome DNA from a Neandertal individual from El Sidrón,...
6.
Karmin M, Saag L, Vicente M, Wilson Sayres M, Jarve M, Talas U, et al.
Genome Res . 2015 Mar; 25(4):459-66. PMID: 25770088
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456...
7.
Mendez F, Veeramah K, Thomas M, Karafet T, Hammer M
Eur J Hum Genet . 2014 Oct; 23(5):564-7. PMID: 25315660
No abstract available.
8.
Carbone L, Harris R, Gnerre S, Veeramah K, Lorente-Galdos B, Huddleston J, et al.
Nature . 2014 Sep; 513(7517):195-201. PMID: 25209798
Gibbons are small arboreal apes that display an accelerated rate of evolutionary chromosomal rearrangement and occupy a key node in the primate phylogeny between Old World monkeys and great apes....
9.
Karafet T, Mendez F, Sudoyo H, Lansing J, Hammer M
Eur J Hum Genet . 2014 Jun; 23(3):369-73. PMID: 24896152
The highly structured distribution of Y-chromosome haplogroups suggests that current patterns of variation may be informative of past population processes. However, limited phylogenetic resolution, particularly of subclades within haplogroup K,...
10.
Mendez F, Krahn T, Schrack B, Krahn A, Veeramah K, Woerner A, et al.
Am J Hum Genet . 2013 Mar; 92(3):454-9. PMID: 23453668
We report the discovery of an African American Y chromosome that carries the ancestral state of all SNPs that defined the basal portion of the Y chromosome phylogenetic tree. We...