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Joseph C F Ng

Explore the profile of Joseph C F Ng including associated specialties, affiliations and a list of published articles. Areas
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Citations 69
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Recent Articles
1.
Ng J, Montamat Garcia G, Stewart A, Blair P, Mauri C, Dunn-Walters D, et al.
Nat Methods . 2023 Nov; 21(5):823-834. PMID: 37932398
Class-switch recombination (CSR) is an integral part of B cell maturation. Here we present sciCSR (pronounced 'scissor', single-cell inference of class-switch recombination), a computational pipeline that analyzes CSR events and...
2.
Harris R, Cheung A, Ng J, Laddach R, Chenoweth A, Crescioli S, et al.
Cancer Res . 2021 Jul; 81(16):4290-4304. PMID: 34224371
In breast cancer, humoral immune responses may contribute to clinical outcomes, especially in more immunogenic subtypes. Here, we investigated B lymphocyte subsets, immunoglobulin expression, and clonal features in breast tumors,...
3.
Chung S, Ng J, Laddach A, Thomas N, Fraternali F
NAR Genom Bioinform . 2021 Mar; 3(1):lqab010. PMID: 33709075
Direct drug targeting of mutated proteins in cancer is not always possible and efficacy can be nullified by compensating protein-protein interactions (PPIs). Here, we establish an pipeline to identify specific...
4.
Ng J, Quist J, Grigoriadis A, Malim M, Fraternali F
Nucleic Acids Res . 2019 Jan; 47(3):1178-1194. PMID: 30624727
APOBEC3 cytidine deaminases are largely known for their innate immune protection from viral infections. Recently, members of the family have been associated with a distinct mutational activity in some cancer...