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Joseph A Frank

Explore the profile of Joseph A Frank including associated specialties, affiliations and a list of published articles. Areas
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Articles 130
Citations 5192
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Recent Articles
1.
Owen J, Negussie A, Burks S, Delgado J, Mikhail A, Rivera J, et al.
Sci Rep . 2024 Sep; 14(1):20929. PMID: 39251665
Transarterial chemoembolization (TACE) is an image-guided minimally invasive treatment for liver cancer which involves delivery of chemotherapy and embolic material into tumor-supplying arteries to block blood flow to a liver...
2.
Dunham C, Frank J
Ultrasound Med Biol . 2024 Jan; 50(4):494-501. PMID: 38218683
Objective: Therapeutic ultrasound remains a highly discussed topic in physical therapy due to uncertainty between treatment regimens and biological benefits. Its impact on aged populations, who are vulnerable to insufficient...
3.
Sarkislali K, Kobayashi K, Saric N, Maeda T, Henmi S, Somaa F, et al.
JACC Basic Transl Sci . 2024 Jan; 8(12):1521-1535. PMID: 38205346
Oxidative/inflammatory stresses due to cardiopulmonary bypass (CPB) cause prolonged microglia activation and cortical dysmaturation, thereby contributing to neurodevelopmental impairments in children with congenital heart disease (CHD). This study found that...
4.
Jung O, Thomas A, Burks S, Dustin M, Frank J, Ferrer M, et al.
Trends Neurosci . 2022 Apr; 45(6):459-470. PMID: 35461727
The blood-brain barrier (BBB) continues to represent one of the most significant challenges for successful drug-based treatments of neurological disease. Mechanical modulation of the BBB using focused ultrasound (FUS) and...
5.
Burks S, Lorsung R, Nagle M, Tu T, Frank J
Theranostics . 2022 Feb; 12(3):1341. PMID: 35154493
[This corrects the article DOI: 10.7150/thno.33876.].
6.
Alptekin A, Khan M, Ara R, Rashid M, Kong F, Parvin M, et al.
J Biomed Nanotechnol . 2021 Jun; 17(6):1170-1183. PMID: 34167630
Exosomes, a component of extracellular vesicles, are shown to carry important small RNAs, mRNAs, protein, and bioactive lipid from parent cells and are found in most biological fluids. Investigators have...
7.
Burks S, Kersch C, Witko J, Pagel M, Sundby M, Muldoon L, et al.
Proc Natl Acad Sci U S A . 2021 Apr; 118(18). PMID: 33906946
Intracarotid arterial hyperosmolar mannitol (ICAHM) blood-brain barrier disruption (BBBD) is effective and safe for delivery of therapeutics for central nervous system malignancies. ICAHM osmotically alters endothelial cells and tight junction...
8.
Cohen G, Chandran P, Lorsung R, Aydin O, Tomlinson L, Rosenblatt R, et al.
Cancers (Basel) . 2021 Apr; 13(7). PMID: 33801627
Focused ultrasound (FUS) has shown promise as a non-invasive treatment modality for solid malignancies. FUS targeting to tumors has been shown to initiate pro-inflammatory immune responses within the tumor microenvironment....
9.
Mastorakos P, Mihelson N, Luby M, Burks S, Johnson K, Hsia A, et al.
Nat Neurosci . 2021 Jan; 24(2):245-258. PMID: 33462481
Cerebrovascular injuries can cause severe edema and inflammation that adversely affect human health. Here, we observed that recanalization after successful endovascular thrombectomy for acute large vessel occlusion was associated with...
10.
Rosenblatt R, Frank J, Burks S
Theranostics . 2021 Jan; 11(2):602-613. PMID: 33391495
Mechanical forces from non-ablative pulsed focused ultrasound (pFUS) generate pro-inflammatory tumor microenvironments (TME), marked by increased cytokines, chemokines, and trophic factors, as well as immune cell infiltration and reduced tumor...