Josep M Aran
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Explore the profile of Josep M Aran including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Luque A, Serrano I, Aran J
Semin Cell Dev Biol
. 2017 Nov;
85:143-152.
PMID: 29155220
Complement and dendritic cells (DCs) share many functional features that drive the outcome of immune-inflammatory processes. Both have a sentinel function, acting as danger sensors specialized for a rapid, comprehensive...
12.
Olivar R, Luque A, Cardenas-Brito S, Naranjo-Gomez M, Blom A, Borras F, et al.
J Immunol
. 2016 Apr;
196(10):4274-90.
PMID: 27076676
The activation of the complement system is a key initiating step in the protective innate immune-inflammatory response against injury, although it may also cause harm if left unchecked. The structurally...
13.
Vento-Tormo R, Company C, Rodriguez-Ubreva J, de la Rica L, Urquiza J, Javierre B, et al.
Genome Biol
. 2016 Jan;
17:4.
PMID: 26758199
Background: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known about how these extracellular factors instruct innate immune...
14.
de Ramon L, Ripoll E, Merino A, Lucia M, Aran J, Perez-Rentero S, et al.
Kidney Int
. 2015 May;
88(3):538-49.
PMID: 25993320
Ischemia-reperfusion occurs in a great many clinical settings and contributes to organ failure or dysfunction. CD154-CD40 signaling in leukocyte-endothelial cell interactions or T-cell activation facilitates tissue inflammation and injury. Here...
15.
Luque A, Farwati A, Crovetto F, Crispi F, Figueras F, Gratacos E, et al.
Sci Rep
. 2014 May;
4:4882.
PMID: 24811064
To assess the usefulness of circulating microRNAs (miRNAs) as non-invasive molecular biomarkers for early prediction of preeclampsia, a differential miRNA profiling analysis was performed in first-trimester pooled sera from 31...
16.
Martinez-Gonzalez I, Cruz M, Moreno R, Morell F, Munoz X, Aran J
Stem Cells Dev
. 2014 May;
23(19):2352-63.
PMID: 24798370
Occupational asthma (OA) is characterized by allergic airway inflammation and hyperresponsiveness, leading to progressive airway remodeling and a concomitant decline in lung function. The management of OA remains suboptimal in...
17.
Ripoll E, Merino A, Herrero-Fresneda I, Aran J, Goma M, Bolanos N, et al.
PLoS One
. 2013 Jun;
8(6):e65068.
PMID: 23799000
Lupus nephritis (LN) is an autoimmune disorder in which co-stimulatory signals have been involved. Here we tested a cholesterol-conjugated-anti-CD40-siRNA in dendritic cells (DC) in vitro and in a model of...
18.
Franquesa M, Hoogduijn M, Reinders M, Eggenhofer E, Engela A, Mensah F, et al.
Transplantation
. 2013 Jun;
96(3):234-8.
PMID: 23759879
The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the...
19.
Martinez-Gonzalez I, Roca O, Masclans J, Moreno R, Salcedo M, Baekelandt V, et al.
Am J Respir Cell Mol Biol
. 2013 May;
49(4):552-62.
PMID: 23656573
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by pulmonary edema attributable to alveolar epithelial-interstitial-endothelial injury, associated with profound inflammation and respiratory dysfunction. The IL-33/IL-1 receptor-like-1...
20.
Olivar R, Luque A, Naranjo-Gomez M, Quer J, Garcia de Frutos P, Borras F, et al.
J Immunol
. 2013 Feb;
190(6):2857-72.
PMID: 23390292
The classical pathway complement regulator C4b-binding protein (C4BP) is composed of two polypeptides (α- and β-chains), which form three plasma oligomers with different subunit compositions (α7β1, α7β0, and α6β1). We...