Josep M Aran
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Explore the profile of Josep M Aran including associated specialties, affiliations and a list of published articles.
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40
Citations
824
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Recent Articles
1.
Checa J, Fiol P, Guevara M, Aran J
Antioxidants (Basel)
. 2024 Mar;
13(3).
PMID: 38539900
Progressive respiratory airway destruction due to unresolved inflammation induced by periodic infectious exacerbation episodes is a hallmark of cystic fibrosis (CF) lung pathology. To clear bacteria, neutrophils release high amounts...
2.
Serrano I, Luque A, Ruiz-Cerulla A, Navas S, Blom A, Rodriguez de Cordoba S, et al.
Pharmacol Res
. 2023 Oct;
197:106948.
PMID: 37806602
The most recent and promising therapeutic strategies for inflammatory bowel disease (IBD) have engaged biologics targeting single effector components involved in major steps of the immune-inflammatory processes, such as tumor...
3.
Serrano I, Luque A, Mitjavila F, Blom A, Rodriguez de Cordoba S, Vega M, et al.
Front Immunol
. 2022 May;
13:883743.
PMID: 35547734
C4b-binding protein (C4BP) is a well-known regulator of the complement system that holds additional and important activities unrelated to complement inhibition. Recently, we have described a novel immunomodulatory activity in...
4.
Checa J, Martinez-Gonzalez I, Maqueda M, Mosquera J, Aran J
Antioxidants (Basel)
. 2021 Dec;
10(12).
PMID: 34943039
Recurrent infection-inflammation cycles in cystic fibrosis (CF) patients generate a highly oxidative environment, leading to progressive destruction of the airway epithelia. The identification of novel modifier genes involved in oxidative...
5.
Hueso M, Mallen A, Sune-Pou M, Aran J, Sune-Negre J, Navarro E
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769025
Non-coding RNAs (ncRNAs) are emerging therapeutic tools but there are barriers to their translation to clinical practice. Key issues concern the specificity of the targets, the delivery of the molecules,...
6.
Checa J, Aran J
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33297418
As aerobic organisms, we are continuously and throughout our lifetime subjected to an oxidizing atmosphere and, most often, to environmental threats. The lung is the internal organ most highly exposed...
7.
Checa J, Aran J
J Inflamm Res
. 2020 Dec;
13:1057-1073.
PMID: 33293849
Since the Great Oxidation Event, about 2.4 billion years ago, the Earth is immersed in an oxidizing atmosphere. Thus, it has been proposed that excess oxygen, originally a waste product...
8.
Luque A, Serrano I, Ripoll E, Malta C, Goma M, Blom A, et al.
Kidney Int
. 2020 Jan;
97(3):551-566.
PMID: 31982108
Lupus nephritis is a chronic autoimmune-inflammatory condition that can lead to end-stage kidney disease. Presently available immunosuppressive treatments for lupus nephritis are suboptimal and can induce significant side effects. Recently,...
9.
Luque A, Farwati A, Krupinski J, Aran J
J Neurosurg
. 2018 Jul;
131(1):72-79.
PMID: 30052155
Objective: Carotid artery atherosclerosis is a major cause of ischemic stroke. However, reliable criteria to identify patients with high-risk carotid plaques beyond the severity of stenosis are still lacking. Circulating...
10.
Serrano I, Luque A, Aran J
Front Immunol
. 2018 May;
9:892.
PMID: 29760704
The acute phase response is generated by an overwhelming immune-inflammatory process against infection or tissue damage, and represents the initial response of the organism in an attempt to return to...