Josefina Ocampo
Overview
Explore the profile of Josefina Ocampo including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
395
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0
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Recent Articles
1.
Beati P, Massimino Stepnicka M, Vilchez Larrea S, Smircich P, Alonso G, Ocampo J
PLoS One
. 2023 Nov;
18(11):e0293809.
PMID: 37988351
In Trypanosoma cruzi DNA is packaged into chromatin by octamers of histone proteins that form nucleosomes. Transcription of protein coding genes in trypanosomes is constitutive producing polycistronic units and gene...
2.
Contreras S, Zambrano Siri R, Rivera E, Cristaldi C, Kamenetzky L, Kim K, et al.
Epigenomes
. 2022 Sep;
6(3).
PMID: 36135316
Subtelomeres (ST) are chromosome regions that separate telomeres from euchromatin and play relevant roles in various biological processes of the cell. While their functions are conserved, ST structure and genetic...
3.
Marr L, Ocampo J, Clark D, Hayes J
Epigenetics Chromatin
. 2021 Jan;
14(1):5.
PMID: 33430969
Background: The vast majority of methods available to characterize genome-wide chromatin structure exploit differences in DNA accessibility to nucleases or chemical crosslinking. We developed a novel method to gauge genome-wide...
4.
Prajapati H, Ocampo J, Clark D
Biology (Basel)
. 2020 Jul;
9(8).
PMID: 32722483
Cellular DNA is packaged into chromatin, which is composed of regularly-spaced nucleosomes with occasional gaps corresponding to active regulatory elements, such as promoters and enhancers, called nucleosome-depleted regions (NDRs). This...
5.
Eisenstatt J, Boeckmann L, Au W, Garcia V, Bursch L, Ocampo J, et al.
G3 (Bethesda)
. 2020 Apr;
10(6):2057-2068.
PMID: 32295767
The evolutionarily conserved centromeric histone H3 variant (Cse4 in budding yeast, CENP-A in humans) is essential for faithful chromosome segregation. Mislocalization of CENP-A to non-centromeric chromatin contributes to chromosomal instability...
6.
Au W, Zhang T, Mishra P, Eisenstatt J, Walker R, Ocampo J, et al.
PLoS Genet
. 2020 Feb;
16(2):e1008597.
PMID: 32032354
Restricting the localization of the histone H3 variant CENP-A (Cse4 in yeast, CID in flies) to centromeres is essential for faithful chromosome segregation. Mislocalization of CENP-A leads to chromosomal instability...
7.
Chereji R, Eriksson P, Ocampo J, Prajapati H, Clark D
Genome Res
. 2019 Sep;
29(12):1985-1995.
PMID: 31511305
DNA accessibility is thought to be of major importance in regulating gene expression. We test this hypothesis using a restriction enzyme as a probe of chromatin structure and as a...
8.
Hamdani O, Dhillon N, Hsieh T, Fujita T, Ocampo J, Kirkland J, et al.
Mol Cell Biol
. 2019 Feb;
39(8).
PMID: 30718362
The genome is packaged and organized in an ordered, nonrandom manner, and specific chromatin segments contact nuclear substructures to mediate this organization. tRNA genes (tDNAs) are binding sites for transcription...
9.
Ocampo J, Chereji R, Eriksson P, Clark D
Genome Res
. 2019 Jan;
29(3):407-417.
PMID: 30683752
Most yeast genes have a nucleosome-depleted region (NDR) at the promoter and an array of regularly spaced nucleosomes phased relative to the transcription start site. We have examined the interplay...
10.
Rawal Y, Chereji R, Valabhoju V, Qiu H, Ocampo J, Clark D, et al.
Mol Cell
. 2018 Apr;
70(2):297-311.e4.
PMID: 29628310
Gcn4 is a yeast transcriptional activator induced by amino acid starvation. ChIP-seq analysis revealed 546 genomic sites occupied by Gcn4 in starved cells, representing ∼30% of Gcn4-binding motifs. Surprisingly, only...