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Josef Cvacka

Explore the profile of Josef Cvacka including associated specialties, affiliations and a list of published articles. Areas
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Articles 131
Citations 996
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Recent Articles
1.
Holub J, Nahlik S, Ruzickova Z, Samsonov M, Samsonov M, Hnyk D, et al.
Angew Chem Int Ed Engl . 2025 Jan; 64(10):e202419677. PMID: 39878376
Wade's rules are a well-established tool for the description of the geometry of inorganic clusters. Among others, they state that a decrease or increase in charge is always accompanied by...
2.
Acikara O, Ataman U, Zidorn C, Cvacka J, Kurtul E, Budesinsky M, et al.
Fitoterapia . 2024 Dec; 180:106328. PMID: 39645051
The antioxidant activity of Scorzonera parviflora Jacq. roots were assessed by measuring their ability to scavenge ABTS and DPPH radicals. Bioactivity-guided fractionation was utilized to identify the compound(s) responsible for...
3.
Kloudova B, Vrkoslav V, Polasek M, Bosakova Z, Cvacka J
Anal Bioanal Chem . 2024 Jul; 416(25):5497-5512. PMID: 39030399
Wax esters play critical roles in biological systems, serving functions from energy storage to chemical signaling. Their diversity is attributed to variations in alcohol and acyl chains, including their length,...
4.
Trojan M, Hroch A, Gruden E, Cvacka J, cejka J, Tavcar G, et al.
RSC Adv . 2024 Jul; 14(31):22326-22334. PMID: 39010913
Nucleophilic fluorination of secondary aliphatic substrates, especially of halides, still remains a challenge. Among the available reagents, TBAT belongs to one of the best choices due to its stability, affordable...
5.
Nemeskalova A, Konvalinkova J, Vagnerova M, Kuchar M, Bucek J, Vrkoslav V, et al.
Talanta . 2024 Jun; 277:126358. PMID: 38879944
Ambient ionization mass spectrometry allows for analysis of samples in their natural state, i.e., with no sample pre-treatment. It can be viewed as a fast, simple, and economical analysis, but...
6.
Raschmanova J, Fazekasova S, Martinkova M, Fabian M, Pilatova M, Cvacka J, et al.
Carbohydr Res . 2024 May; 541:109158. PMID: 38796901
Straightforward access to enantiomerically pure 3,4-diamino-3,4-dideoxyphytosphingosines, as novel analogues of natural d-ribo-phytosphingosine was accomplished, starting from two available chirons: dimethyl l-tartrate and d-isoascorbic acid. A sequential Overman rearrangement followed by...
7.
Strnad S, Vrkoslav V, Mengr A, Fabian O, Rybacek J, Kubanek M, et al.
Analyst . 2024 Apr; 149(11):3152-3160. PMID: 38630503
Cholesterol plays an important biological role in the body, and its disruption in homeostasis and synthesis has been implicated in several diseases. Mapping the locations of cholesterol is crucial for...
8.
Trojan M, Kucnirova K, Bouzkova S, Cvacka J, cejka J, Tavcar G, et al.
Org Biomol Chem . 2024 Jan; 22(5):1047-1056. PMID: 38197465
TBAT (tetrabutylammonium difluorotriphenylsilicate) is an excellent homogeneous nucleophilic fluorination reagent, but a high excess of the reagent was reported to be essential. We hence optimized the reaction conditions and compared...
9.
Loncaric D, Movahedifar F, Radek Stocek J, Dracinsky M, Cvacka J, Guan S, et al.
Chem Sci . 2023 Sep; 14(35):9258-9266. PMID: 37712024
Cucurbit[7]uril (CB[7]) encapsulates adamantyl and trimethylsilyl substituents of positively charged guests in dimethyl sulfoxide (DMSO). Unlike in water or deuterium oxide, addition of a selection of alkali and alkali-earth cations...
10.
Vlachova M, Tran V, cerveny J, Dolnicek F, Petraskova L, Pelantova H, et al.
Chem Commun (Camb) . 2023 Aug; 59(69):10404-10407. PMID: 37551910
Elevated levels of galectin-3 are associated with tumorigenesis. Its inhibition with high-affinity carbohydrate ligands opens new therapeutic routes. Targeting of intracellular galectin-3 is challenging for polar inhibitors like carbohydrates. We...