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Josef Bischofberger

Explore the profile of Josef Bischofberger including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 2665
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Recent Articles
1.
Trovo L, Kouvaros S, Schwenk J, Fernandez-Fernandez D, Fritzius T, Rem P, et al.
EMBO Rep . 2024 May; 25(6):2610-2634. PMID: 38698221
GABA receptors (GBRs), the G protein-coupled receptors for GABA, regulate synaptic transmission throughout the brain. A main synaptic function of GBRs is the gating of Cav2.2-type Ca channels. However, the...
2.
Vestring S, Dorner A, Scholliers J, Ehrenberger K, Kiss A, Arenz L, et al.
Transl Psychiatry . 2024 Jan; 14(1):18. PMID: 38195548
The partial N-methyl-D-aspartate receptor (NMDAR) agonist D-Cycloserine (DCS) has been evaluated for the treatment of a wide variety of psychiatric disorders, including dementia, schizophrenia, depression and for the augmentation of...
3.
Traunmuller L, Schulz J, Ortiz R, Feng H, Furlanis E, Gomez A, et al.
Cell Rep . 2023 Mar; 42(3):112173. PMID: 36862556
The specification of synaptic properties is fundamental for the function of neuronal circuits. "Terminal selector" transcription factors coordinate terminal gene batteries that specify cell-type-specific properties. Moreover, pan-neuronal splicing regulators have...
4.
Hauser D, Behr K, Konno K, Schreiner D, Schmidt A, Watanabe M, et al.
Neuron . 2022 May; 110(13):2094-2109.e10. PMID: 35550065
The diversification of cell adhesion molecules by alternative splicing is proposed to underlie molecular codes for neuronal wiring. Transcriptomic approaches mapped detailed cell-type-specific mRNA splicing programs. However, it has been...
5.
Lodge M, Hernandez M, Schulz J, Bischofberger J
Cell Rep . 2021 Oct; 37(1):109768. PMID: 34610304
GABA can depolarize immature neurons close to the action potential (AP) threshold in development and adult neurogenesis. Nevertheless, GABAergic synapses effectively inhibit AP firing in newborn granule cells of the...
6.
Schulz J, Kay J, Bischofberger J, Larkum M
Front Cell Neurosci . 2021 Sep; 15:718413. PMID: 34512268
Synergistic interactions between independent synaptic input streams may fundamentally change the action potential (AP) output. Using partial information decomposition, we demonstrate here a substantial contribution of synergy between somatic and...
7.
Lodge M, Bischofberger J
Behav Brain Res . 2019 Jun; 372:112036. PMID: 31201871
In the adult hippocampus new neurons are continuously generated throughout life and integrate into the existing network via the formation of thousands of new synapses. Adult-born granule cells are known...
8.
Schulz J, Knoflach F, Hernandez M, Bischofberger J
J Neurosci . 2019 Apr; 39(26):5210-5221. PMID: 31000585
Down syndrome (DS) or Trisomy 21 is a developmental disorder leading to cognitive deficits, including disruption of hippocampus-dependent learning and memory. Enhanced inhibition has been suggested to underlie these deficits...
9.
Schulz J, Knoflach F, Hernandez M, Bischofberger J
Nat Commun . 2018 Sep; 9(1):3576. PMID: 30177704
Dendrite-targeting GABAergic interneurons powerfully control postsynaptic integration, synaptic plasticity, and learning. However, the mechanisms underlying the efficient GABAergic control of dendritic electrogenesis are not well understood. Using subtype-selective blockers for...
10.
Bolz L, Heigele S, Bischofberger J
Brain Plast . 2018 May; 1(1):129-141. PMID: 29765837
Running increases adult neurogenesis and improves pattern separation in various memory tasks including context fear conditioning or touch-screen based spatial learning. However, it is unknown whether pattern separation is improved...