Josef Bischofberger
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Explore the profile of Josef Bischofberger including associated specialties, affiliations and a list of published articles.
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44
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2665
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Recent Articles
11.
Normann C, Frase S, Haug V, von Wolff G, Clark K, Munzer P, et al.
Biol Psychiatry
. 2017 Nov;
84(1):55-64.
PMID: 29174591
Background: Long-term synaptic plasticity is a basic ability of the brain to dynamically adapt to external stimuli and regulate synaptic strength and ultimately network function. It is dysregulated by behavioral...
12.
Li L, Sultan S, Heigele S, Schmidt-Salzmann C, Toni N, Bischofberger J
Elife
. 2017 Aug;
6.
PMID: 28826488
In adult neurogenesis young neurons connect to the existing network via formation of thousands of new synapses. At early developmental stages, glutamatergic synapses are sparse, immature and functionally 'silent', expressing...
13.
Fedele S, Collo G, Behr K, Bischofberger J, Muller S, Kunath T, et al.
Sci Rep
. 2017 Jul;
7(1):6036.
PMID: 28729666
Human induced pluripotent stem cells (hiPSCs) are invaluable to study developmental processes and disease mechanisms particularly in the brain. hiPSCs can be differentiated into mature and functional dopaminergic (DA) neurons....
14.
Iijima Y, Behr K, Iijima T, Biemans B, Bischofberger J, Scheiffele P
Sci Rep
. 2016 Jun;
6:27400.
PMID: 27264355
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders characterized by impairments in social interactions and stereotyped behaviors. Valproic acid (VPA) is frequently used to treat epilepsy and...
15.
Costa V, Aigner S, Vukcevic M, Sauter E, Behr K, Ebeling M, et al.
Cell Rep
. 2016 Apr;
15(1):86-95.
PMID: 27052171
Hyperfunction of the mTORC1 pathway has been associated with idiopathic and syndromic forms of autism spectrum disorder (ASD), including tuberous sclerosis, caused by loss of either TSC1 or TSC2. It...
16.
Heigele S, Sultan S, Toni N, Bischofberger J
Nat Neurosci
. 2016 Jan;
19(2):263-70.
PMID: 26752162
Newly generated young neurons in the adult hippocampus receive GABAergic synaptic inputs, which are crucial for activity-dependent survival and functional maturation between 1-3 weeks after mitosis. We found synaptically driven...
17.
Sultan S, Li L, Moss J, Petrelli F, Casse F, Gebara E, et al.
Neuron
. 2015 Nov;
88(5):957-972.
PMID: 26606999
Adult neurogenesis is regulated by the neurogenic niche, through mechanisms that remain poorly defined. Here, we investigated whether niche-constituting astrocytes influence the maturation of adult-born hippocampal neurons using two independent...
18.
Pohle J, Bischofberger J
J Physiol
. 2014 Sep;
592(22):4931-49.
PMID: 25239458
Although Ca(2+) is critically important in activity-dependent neuronal development, not much is known about the regulation of dendritic Ca(2+) signals in developing neurons. Here, we used ratiometric Ca(2+) imaging to...
19.
Giachino C, Barz M, Tchorz J, Tome M, Gassmann M, Bischofberger J, et al.
Development
. 2013 Nov;
141(1):83-90.
PMID: 24284211
Adult neurogenesis is tightly regulated through the interaction of neural stem/progenitor cells (NSCs) with their niche. Neurotransmitters, including GABA activation of GABAA receptor ion channels, are important niche signals. We...
20.
Schmidt-Salzmann C, Li L, Bischofberger J
J Physiol
. 2013 Nov;
592(1):125-40.
PMID: 24218546
In the mammalian hippocampus, new granule cells are continuously generated throughout life. Although it is well known that they rapidly form several thousand new glutamatergic synapses, the underlying mechanisms are...