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Jose Villadangos

Explore the profile of Jose Villadangos including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 388
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Recent Articles
1.
Babon J, Stockwell D, DiRago L, Zhang J, Laktyushin A, Villadangos J, et al.
Biochem J . 2019 Sep; 476(19):2869-2882. PMID: 31488575
Interleukin 6 (IL6) is a cytokine that regulates a number of important immune and inflammatory pathways. We used the ability of IL6 to inhibit the clonal proliferation of the mouse...
2.
Roquilly A, Broquet A, Jacqueline C, Masson D, Segain J, Braudeau C, et al.
Crit Care Med . 2014 Oct; 42(12):e752-61. PMID: 25289930
Objective: Trauma induces a state of immunosuppression, which is responsible for the development of nosocomial infections. Hydrocortisone reduces the rate of pneumonia in patients with trauma. Because alterations of dendritic...
3.
Wakim L, Woodward-Davis A, Liu R, Hu Y, Villadangos J, Smyth G, et al.
J Immunol . 2012 Aug; 189(7):3462-71. PMID: 22922816
Tissue resident memory (Trm) CD8 T cells represent a newly described memory T cell population. We have previously characterized a population of Trm cells that persists within the brain after...
4.
Rizzitelli A, Meuter S, Ramos J, Bird C, Mintern J, Mangan M, et al.
Immunol Cell Biol . 2012 Jul; 90(9):841-51. PMID: 22801574
Serpinb9 (Sb9, also called Spi6) is an intracellular inhibitor of granzyme B (GrB) that protects activated cytotoxic lymphocytes from apoptosis. We show here that the CD8(+) subset of splenic dendritic...
5.
Vremec D, OKeeffe M, Wilson A, Ferrero I, Koch U, Radtke F, et al.
Innate Immun . 2010 May; 17(3):338-52. PMID: 20501515
Dendritic cells (DCs) serve as a link between the innate and adaptive immune systems. The activation state of DCs is crucial in this role. However, when DCs are isolated from...
6.
Schnurr M, Chen Q, Shin A, Chen W, Toy T, Jenderek C, et al.
Blood . 2004 Nov; 105(6):2465-72. PMID: 15546948
Dendritic cells (DCs) are being evaluated for cancer immunotherapy due to their unique ability to induce tumor-directed T-cell responses. Here we report that the type of human DC, the mode...
7.
Fiebiger E, Maehr R, Villadangos J, Weber E, Erickson A, Bikoff E, et al.
J Exp Med . 2002 Nov; 196(9):1263-9. PMID: 12417635
Secretion of proteases is critical for degradation of the extracellular matrix during an inflammatory response. Cathepsin (Cat) S and L are the major elastinolytic cysteine proteases in mouse macrophages. A...