Jose Miguel Rodriguez-Frade
Overview
Explore the profile of Jose Miguel Rodriguez-Frade including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
873
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Recent Articles
1.
Rodriguez-Frade J, Gonzalez-Granado L, Santiago C, Mellado M
Front Immunol
. 2024 Jul;
15:1406532.
PMID: 39035006
Heterozygous autosomal dominant mutations in the CXCR4 gene cause WHIM syndrome, a severe combined immunodeficiency disorder. The mutations primarily affect the C-terminal region of the CXCR4 chemokine receptor, specifically several...
2.
Cayuela Lopez A, Garcia-Cuesta E, Gardeta S, Rodriguez-Frade J, Mellado M, Gomez-Pedrero J, et al.
Biol Imaging
. 2024 Mar;
3:e18.
PMID: 38510172
Current live-cell imaging techniques make possible the observation of live events and the acquisition of large datasets to characterize the different parameters of the visualized events. They provide new insights...
3.
Soler Palacios B, Villares R, Lucas P, Rodriguez-Frade J, Cayuela A, Piccirillo J, et al.
Front Immunol
. 2023 Jul;
14:1200259.
PMID: 37475858
Introduction: Macrophages are a heterogeneous population of innate immune cells that support tissue homeostasis through their involvement in tissue development and repair, and pathogen defense. Emerging data reveal that metabolism...
4.
Gardeta S, Garcia-Cuesta E, DAgostino G, Soler Palacios B, Quijada-Freire A, Lucas P, et al.
Front Immunol
. 2022 Jul;
13:925559.
PMID: 35903108
Sphingolipids, ceramides and cholesterol are integral components of cellular membranes, and they also play important roles in signal transduction by regulating the dynamics of membrane receptors through their effects on...
5.
Garcia-Cuesta E, Rodriguez-Frade J, Gardeta S, DAgostino G, Martinez P, Soler Palacios B, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(21):e2119483119.
PMID: 35588454
Chemokine receptor nanoscale organization at the cell membrane is orchestrated by the actin cytoskeleton and influences cell responses. Using single-particle tracking analysis we show that CXCR4R334X, a truncated mutant chemokine...
6.
Marcos-Jimenez A, Sanchez-Alonso S, Alcaraz-Serna A, Esparcia L, Lopez-Sanz C, Sampedro-Nunez M, et al.
Eur J Immunol
. 2020 Nov;
51(3):634-647.
PMID: 33251605
SARS-CoV-2 infection causes an abrupt response by the host immune system, which is largely responsible for the outcome of COVID-19. We investigated whether the specific immune responses in the peripheral...
7.
Soler Palacios B, Nieto C, Fajardo P, de la Aleja A, Andres N, Dominguez-Soto A, et al.
J Immunol
. 2020 Jun;
205(3):776-788.
PMID: 32591394
Growth hormone (GH), a pleiotropic hormone secreted by the pituitary gland, regulates immune and inflammatory responses. In this study, we show that GH regulates the phenotypic and functional plasticity of...
8.
DAgostino G, Garcia-Cuesta E, Gomariz R, Rodriguez-Frade J, Mellado M
Biochem Biophys Res Commun
. 2020 Mar;
528(2):347-358.
PMID: 32145914
The chemokines receptor family are membrane-expressed class A-specific seven-transmembrane receptors linked to G proteins. Through interaction with the corresponding ligands, the chemokines, they induce a wide variety of cellular responses...
9.
Garcia-Cuesta E, Santiago C, Vallejo-Diaz J, Juarranz Y, Rodriguez-Frade J, Mellado M
Front Endocrinol (Lausanne)
. 2019 Sep;
10:585.
PMID: 31507535
Chemokine receptors are members of the G protein-coupled receptor superfamily. These receptors are intimately involved in cell movement, and thus play a critical role in several physiological and pathological situations...
10.
Martinez-Munoz L, Rodriguez-Frade J, Barroso R, Sorzano C, Torreno-Pina J, Santiago C, et al.
Mol Cell
. 2018 Sep;
71(5):873.
PMID: 30193101
No abstract available.