Jose Manuel Lopes
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Explore the profile of Jose Manuel Lopes including associated specialties, affiliations and a list of published articles.
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108
Citations
2299
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Recent Articles
1.
Pereira A, Pedrosa S, Moreira R, Leao-Teles E, Lopes J, Magalhaes A
Cornea
. 2025 Mar;
PMID: 40079783
Purpose: Maroteaux-Lamy syndrome (MPSVI) is a rare lysosomal storage disorder caused by an Arylsulfatase B (ARSB) deficiency, leading to dermatan sulfate and chondroitin-4-sulfate accumulation. It manifests various systemic clinical features....
2.
Meireles S, Dias C, Martins D, Marques A, Dias N, Pacheco-Figueiredo L, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335667
Background: Molecular profiling in upper tract urothelial carcinoma (UTUC) with synchronous or metachronous urothelial bladder cancer (UBC) is scarce. We intended to assess immunohistochemical (IHC) and genetic differences between UTUC-only...
3.
Gaspar T, Jesus T, Azevedo M, Macedo S, Soares M, Martins R, et al.
Cancers (Basel)
. 2023 Jun;
15(11).
PMID: 37296979
Atrx loss was recently ascertained as insufficient to drive pancreatic neuroendocrine tumour (PanNET) formation in mice islets. We have identified a preponderant role of Atrx in the endocrine dysfunction in...
4.
Castanheira A, Boaventura P, Vieira F, Soares P, Mota A, Lopes J
Porto Biomed J
. 2023 May;
7(5):e190.
PMID: 37213919
Background: Cutaneous basal cell carcinoma (cBCC) incidence has been increasing, but there are no available data on its epidemiological, clinical, and pathological patterns in Northeast Portugal. cBCC is mainly located...
5.
Meireles S, Dias N, Martins D, Dias C, Goncalves M, Silva J, et al.
Diagnostics (Basel)
. 2023 Jan;
13(1).
PMID: 36611446
Accurately predicting the clinical prognosis of upper tract urothelial carcinoma (UTUC) seems crucial. We evaluated the effect of the involvement of urothelial bladder carcinoma (UBC) as a potential prognostic factor...
6.
Gaspar T, Lopes J, Soares P, Vinagre J
Endocr Relat Cancer
. 2022 Oct;
29(12):R191-R208.
PMID: 36197786
Pancreatic neuroendocrine neoplasms (PanNENs) are rare and clinically challenging entities. At the molecular level, PanNENs' genetic profile is well characterized, but there is limited knowledge regarding the contribution of the...
7.
Gaspar T, Macedo S, Sa A, Soares M, Rodrigues D, Sousa M, et al.
Cancers (Basel)
. 2022 Aug;
14(16).
PMID: 36010860
ATRX is a chromatin remodeller that maintains telomere homeostasis. Loss of is described in approximately 10% of pancreatic neuroendocrine tumours (PanNETs) and associated with poorer prognostic features. Here, we present...
8.
Nunes B, Populo H, Lopes J, Reis M, Nascimento G, Nascimento A, et al.
Genes (Basel)
. 2022 Apr;
13(4).
PMID: 35456480
Gap junction intercellular communication (GJIC) is considered a key mechanism in the regulation of tissue homeostasis. GJIC structures are organized in two transmembrane channels, with each channel formed by connexins...
9.
Garrido I, Rodrigues-Pinto E, Pedrosa S, Lopes J, Macedo G
Am J Gastroenterol
. 2022 Jan;
117(4):531.
PMID: 35020620
No abstract available.
10.
Martins F, Martins C, Fernandes M, Andrade M, Lopes J, Soares P, et al.
Dermatology
. 2021 Sep;
238(3):507-516.
PMID: 34569488
Background: While BRAF mutations seem important for early melanomagenesis, mutations in the TERT promoter (TERTp) are related to metastasis. Yet, in conventional melanoma management, risk stratification does not depend on...