Jose M Gallego-Escuredo
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Explore the profile of Jose M Gallego-Escuredo including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Domingo P, Gracia Mateo M, Villarroya J, Cereijo R, Torres F, Domingo J, et al.
J Clin Med
. 2022 Feb;
11(3).
PMID: 35160008
Objective: People living with HIV (PLWH) have an increased cardiovascular risk (CVR) owing to dyslipidemia, insulin resistance, metabolic syndrome, and HIV/combination antiretroviral therapy (cART)-associated lipodystrophy (HALS). Atherosclerosis and inflammation are...
2.
Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
Villarroya J, Gallego-Escuredo J, Delgado-Angles A, Cairo M, Moure R, Mateo M, et al.
Aging Cell
. 2018 Jul;
17(5):e12822.
PMID: 30043445
Fibroblast growth factor 21 (FGF21) has been proposed to be an antiaging hormone on the basis of experimental studies in rodent models. However, circulating FGF21 levels are increased with aging...
3.
Moure R, Domingo P, Villarroya J, Gasa L, Gallego-Escuredo J, Quesada-Lopez T, et al.
Antimicrob Agents Chemother
. 2018 Apr;
62(6).
PMID: 29661866
Following antiretroviral therapy, HIV-infected patients show increased circulating levels of the antidiabetic hormone fibroblast growth factor 21 (FGF21). In contrast, the expression of the FGF21-obligatory coreceptor β-Klotho (KLB) is reduced...
4.
Gallego-Escuredo J, Lamarca M, Villarroya J, Domingo J, Mateo M, Gutierrez M, et al.
Metabolism
. 2017 May;
71:163-170.
PMID: 28521869
Background: Fibroblast growth factor-21 (FGF21) has emerged as an important regulator of glucose, lipid, and body weight homeostasis. However, recent experimental studies have reported that increased FGF21 levels may lead...
5.
Alvarez-Sola G, Uriarte I, Latasa M, Fernandez-Barrena M, Urtasun R, Elizalde M, et al.
Gut
. 2017 Jan;
66(10):1818-1828.
PMID: 28119353
Objective: Fibroblast growth factor 15/19 (FGF15/19), an enterokine that regulates synthesis of hepatic bile acids (BA), has been proposed to influence fat metabolism. Without FGF15/19, mouse liver regeneration after partial...
6.
Moure R, Domingo P, Gallego-Escuredo J, Villarroya J, Gutierrez M, Mateo M, et al.
Antiviral Res
. 2016 May;
132:59-65.
PMID: 27216995
Elvitegravir is a recently developed integrase inhibitor used for antiretroviral treatment of HIV infection. Secondary effects, including disturbances in lipid metabolism and, ultimately, in adipose tissue distribution and function, are...
7.
Gomez-Ambrosi J, Gallego-Escuredo J, Catalan V, Rodriguez A, Domingo P, Moncada R, et al.
Clin Nutr
. 2016 May;
36(3):861-868.
PMID: 27188262
Background & Aims: Fibroblast growth factor 19 (FGF19) and 21 (FGF21) have emerged as key regulators of energy homeostasis. Our aim was to analyze the impact of weight loss (WL)...
8.
Di Franco A, Guasti D, Squecco R, Mazzanti B, Rossi F, Idrizaj E, et al.
Stem Cells
. 2016 Feb;
34(6):1679-91.
PMID: 26866833
The potential therapeutic applications of targeting brown adipose tissue open new clinical avenues in fighting against metabolic pathologies. However, due to the limited extension in adult humans of brown depots,...
9.
Domingo P, Lamarca M, Gallego-Escuredo J, Torres F, Domingo J, Villarroya J, et al.
J Antimicrob Chemother
. 2015 Feb;
70(6):1825-32.
PMID: 25700720
Objectives: Dyslipidaemia, insulin resistance, metabolic syndrome and HIV/HAART-associated lipodystrophy syndrome (HALS) are common comorbidities in HIV-1-infected patients, which may increase cardiovascular risk. Fibroblast growth factor 23 (FGF23) is a bone-derived...
10.
Hondares E, Gallego-Escuredo J, Flachs P, Frontini A, Cereijo R, Goday A, et al.
Metabolism
. 2013 Dec;
63(3):312-7.
PMID: 24369918
Objective: In rodents, brown (BAT) and white (WAT) adipose tissues are targets and expression sites for fibroblast growth factor-21 (FGF21). In contrast, human WAT expresses negligible levels of FGF21. We...