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Jose M Fernandez-Real

Explore the profile of Jose M Fernandez-Real including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 1478
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Recent Articles
1.
Lluch A, Latorre J, Oliveras-Canellas N, Fernandez-Sanchez A, Moreno-Navarrete J, Castells-Nobau A, et al.
Mol Metab . 2024 Oct; 90:102040. PMID: 39362599
Background: Long non-coding RNAs (lncRNAs) can perform tasks of key relevance in fat cells, contributing, when defective, to the burden of obesity and its sequelae. Here, scrutiny of adipose tissue...
2.
Lluch A, Latorre J, Serena-Maione A, Espadas I, Caballano-Infantes E, Moreno-Navarrete J, et al.
Nat Commun . 2023 Aug; 14(1):5106. PMID: 37607954
Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention has been given to its role in...
3.
Lluch A, Veiga S, Latorre J, Moreno-Navarrete J, Bonifaci N, Nguyen V, et al.
JCI Insight . 2022 Jun; 7(14). PMID: 35737463
The ribosomal protein S6 kinase 1 (S6K1) is a relevant effector downstream of the mammalian target of rapamycin complex 1 (mTORC1), best known for its role in the control of...
4.
Rodriguez-Barrueco R, Latorre J, Devis-Jauregui L, Lluch A, Bonifaci N, Llobet F, et al.
Adv Sci (Weinh) . 2021 Dec; 9(4):e2104759. PMID: 34898027
The H19X-encoded miR-424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this...
5.
Izquierdo A, Carreira M, Boughanem H, Moreno-Navarrete J, Nicoletti C, Oliver P, et al.
Eur J Clin Invest . 2021 Sep; 52(2):e13685. PMID: 34582564
Background: Obesity was consistently associated with a poor prognosis in patients with COVID-19. Epigenetic mechanisms were proposed as the link between obesity and comorbidities risk. Aim: To evaluate the methylation...
6.
Fernandez-Aranda F, Munguia L, Mestre-Bach G, Steward T, Etxandi M, Baenas I, et al.
Eur Eat Disord Rev . 2020 Sep; 28(6):871-883. PMID: 32954595
Confinement during the COVID-19 pandemic is expected to have a serious and complex impact on the mental health of patients with an eating disorder (ED) and of patients with obesity....
7.
Izquierdo A, Carreira M, Rodriguez-Carnero G, Fernandez-Quintela A, Sueiro A, Martinez-Olmos M, et al.
Int J Obes (Lond) . 2020 Jun; 45(1):206-216. PMID: 32546857
Background/objectives: Survivin is an oncogene associated with a decrease in apoptosis, an increase in tumor growth, and poor clinical outcome of diverse malignancies. A correlation between obesity, cancer, and survivin...
8.
Latorre J, Ortega F, Linares-Pose L, Moreno-Navarrete J, Lluch A, Comas F, et al.
EBioMedicine . 2020 Mar; 53:102697. PMID: 32143184
Background: While the impact of metformin in hepatocytes leads to fatty acid (FA) oxidation and decreased lipogenesis, hepatic microRNAs (miRNAs) have been associated with fat overload and impaired metabolism, contributing...
9.
Santamaria-Martos F, Benitez I, Ortega F, Zapater A, Giron C, Pinilla L, et al.
Sci Rep . 2019 Sep; 9(1):13456. PMID: 31530881
Evaluation of microRNAs (miRNAs) could allow characterization of the obstructive sleep apnea (OSA) and help diagnose it more accurately. We aimed to examine circulating miRNA profiles to establish the differences...
10.
Ortega F, Moreno-Navarrete J, Mercader J, Gomez-Serrano M, Garcia-Santos E, Latorre J, et al.
FASEB J . 2019 May; 33(8):9656-9671. PMID: 31145872
During adipogenesis, preadipocytes' cytoskeleton reorganizes in parallel with lipid accumulation. Failure to do so may impact the ability of adipose tissue (AT) to shift between lipid storage and mobilization. Here,...