Jose Luis de la Pompa
Overview
Explore the profile of Jose Luis de la Pompa including associated specialties, affiliations and a list of published articles.
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77
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3777
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Recent Articles
1.
de la Pompa J
Science
. 2025 Mar;
387(6739):1151-1152.
PMID: 40080579
Membrane projections from muscle cells enable signaling in the developing mouse heart.
2.
Henderson D, Alqahtani A, Chaudhry B, Cook A, Eley L, Houyel L, et al.
Dis Model Mech
. 2024 Nov;
17(11).
PMID: 39575509
Congenital heart defects (CHDs), the most common congenital anomalies, are considered to have a significant genetic component. However, despite considerable efforts to identify pathogenic genes in patients with CHDs, few...
3.
Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, et al.
Nat Commun
. 2024 Oct;
15(1):8602.
PMID: 39366945
Extensive genetic studies have elucidated cardiomyocyte differentiation and associated gene networks using single-cell RNA-seq, yet the intricate transcriptional mechanisms governing cardiac conduction system (CCS) development and working cardiomyocyte differentiation remain...
4.
Pineiro-Sabaris R, MacGrogan D, de la Pompa J
Dis Model Mech
. 2024 Sep;
17(9).
PMID: 39253784
The cardiac outflow tract (OFT) transiently links the ventricles to the aortic sac and forms the arterial valves. Abnormalities in these valves, such as bicuspid aortic valve (BAV), are common...
5.
Fernandez-Tocino M, Pun-Garcia A, Gomez M, Clemente-Moragon A, Oliver E, Villena-Gutierrez R, et al.
Basic Res Cardiol
. 2024 Aug;
119(5):773-794.
PMID: 39134663
β3-Adrenergic receptor (β3AR) agonists have been shown to protect against ischemia-reperfusion injury (IRI). Since β3ARs are present both in cardiomyocytes and in endothelial cells, the cellular compartment responsible for this...
6.
Pineiro-Sabaris R, MacGrogan D, de la Pompa J
J Cardiovasc Dev Dis
. 2024 Jul;
11(7).
PMID: 39057643
Genome-wide association studies and experimental mouse models implicate the and genes in congenital heart disease (CHD). Their close physical proximity and conserved synteny suggest that these two genes might be...
7.
Luna-Zurita L, Flores-Garza B, Grivas D, Siguero-Alvarez M, de la Pompa J
Circ Res
. 2023 Nov;
133(12):1022-1039.
PMID: 37961886
Background: The endocardium is a crucial signaling center for cardiac valve development and maturation. Genetic analysis has identified several human endocardial genes whose inactivation leads to bicuspid aortic valve formation...
8.
Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez M, MacGrogan D, de la Pompa J
Circ Res
. 2023 Oct;
133(11):927-943.
PMID: 37846569
Background: Cardiac ventricles provide the contractile force of the beating heart throughout life. How the primitive endocardium-layered myocardial projections called trabeculae form and mature into the adult ventricles is of...
9.
Tessler I, Albuisson J, Pineiro-Sabaris R, Verstraeten A, Kamber Kaya H, Siguero-Alvarez M, et al.
JAMA Cardiol
. 2023 Jul;
8(8):721-731.
PMID: 37405741
Importance: Nonsyndromic bicuspid aortic valve (nsBAV) is the most common congenital heart valve malformation. BAV has a heritable component, yet only a few causative genes have been identified; understanding BAV...
10.
Escriba R, Larranaga-Moreira J, Richaud-Patin Y, Pourchet L, Lazis I, Jimenez-Delgado S, et al.
Circ Res
. 2023 Jun;
133(2):108-119.
PMID: 37317833
Background: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a frequent cause of heart failure and sudden cardiac death. Our understanding of the genetic bases and pathogenic...