Jose L F C Lima
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Explore the profile of Jose L F C Lima including associated specialties, affiliations and a list of published articles.
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160
Citations
1639
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Recent Articles
1.
Martins T, Silva V, Silva A, Lima J, Fernandes E, Ribeiro D
Med Chem
. 2020 Dec;
18(1):88-96.
PMID: 33380306
Aims: This study evaluates the ability of chalcones to scavenge hypochlorous acid (HOCl) and modulate oxidative burst. Background: The chemistry of chalcones has long been a matter of interest to...
2.
Ramos I, Marques S, Magalhaes L, Barreiros L, Reis S, Lima J, et al.
Talanta
. 2019 Jul;
204:542-547.
PMID: 31357331
The repeatable immobilization of molecular recognition elements onto particle surfaces has a strong impact on the outcomes of affinity-based assays. In this work, an automatic method for the immobilization of...
3.
Soares T, Rodrigues D, Sarraguca M, Rocha S, Lima J, Ribeiro D, et al.
Oxid Med Cell Longev
. 2019 Feb;
2019:7198484.
PMID: 30733852
The purpose of an experimental design is to improve the productivity of experimentation. It is an efficient procedure for planning experiments, so the data obtained can be analyzed to yield...
4.
Ribeiro D, Freitas M, Rocha S, Lima J, Carvalho F, Fernandes E
Cells
. 2018 Nov;
7(11).
PMID: 30423935
In neutrophils, intracellular Ca levels are regulated by several transporters and pathways, namely SERCA [sarco(endo)plasmic reticulum Ca-ATPase], SOCE (store-operated calcium entry), and ROCE (receptor-operated calcium entry). However, the exact mechanisms...
5.
Ribeiro D, Proenca C, Rocha S, Lima J, Carvalho F, Fernandes E, et al.
Curr Med Chem
. 2018 Feb;
25(28):3374-3412.
PMID: 29446723
Inflammatory Bowel Diseases (IBD) comprised of two disorders of idiopathic chronic intestinal inflammation that affect about three million people worldwide: Crohn's disease and ulcerative colitis. Nowadays, the first-line of treatment...
6.
Ramos I, Magalhaes L, Barreiros L, Reis S, Lima J, Segundo M
Anal Bioanal Chem
. 2017 Sep;
410(3):981-988.
PMID: 28889209
Immunoglobulin G (IgG) represents the major fraction of antibodies in healthy adult human serum, and deviations from physiological levels are a generic marker of disease corresponding to different pathologies. Therefore,...
7.
Alves A, Ribeiro D, Horta M, Lima J, Nunes C, Reis S
J R Soc Interface
. 2017 Sep;
14(133).
PMID: 28855387
Daunorubicin is extensively used in chemotherapy for diverse types of cancer. Over the years, evidence has suggested that the mechanisms by which daunorubicin causes cytotoxic effects are also associated with...
8.
Alves A, Magarkar A, Horta M, Lima J, Bunker A, Nunes C, et al.
Sci Rep
. 2017 Jul;
7(1):6343.
PMID: 28740256
Despite doxorubicin being commonly used in chemotherapy there still remain significant holes in our knowledge regarding its delivery efficacy and an observed resistance mechanism that is postulated to involve the...
9.
Proenca C, Ribeiro D, Soares T, Tome S, Silva A, Lima J, et al.
Inflammation
. 2017 Apr;
40(4):1155-1165.
PMID: 28405852
Flavonoids are known to react with neutrophil-generated hypochlorous acid (HOCl) at inflammation loci to form stable mono- and dichlorinated products. Some of these products have been shown to retain or...
10.
Alves A, Ribeiro D, Horta M, Lima J, Nunes C, Reis S
Biochim Biophys Acta Biomembr
. 2017 Feb;
1859(5):941-948.
PMID: 28153496
The present work aimed to study the interactions between the anticancer drug daunorubicin and lipid membrane mimetic models of cancer cells composed by their most representative classes of phospholipids, with...