Jose I Jimenez
Overview
Explore the profile of Jose I Jimenez including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
681
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Recent Articles
11.
Lastiri-Pancardo G, Mercado-Hernandez J, Kim J, Jimenez J, Utrilla J
Nat Chem Biol
. 2020 Jul;
16(9):1026-1033.
PMID: 32661378
Engineering resource allocation in biological systems is an ongoing challenge. Organisms allocate resources for ensuring survival, reducing the productivity of synthetic biology functions. Here we present a new approach for...
12.
Kim J, Darlington A, Salvador M, Utrilla J, Jimenez J
Curr Opin Biotechnol
. 2019 Oct;
62:29-37.
PMID: 31580950
Bacterial cells have a limited number of resources that can be allocated for gene expression. The intracellular competition for these resources has an impact on the cell physiology. Bacteria have...
13.
Salvador M, Abdulmutalib U, Gonzalez J, Kim J, Smith A, Faulon J, et al.
Genes (Basel)
. 2019 May;
10(5).
PMID: 31100963
Plastics have become an important environmental concern due to their durability and resistance to degradation. Out of all plastic materials, polyesters such as polyethylene terephthalate (PET) are amenable to biological...
14.
Darlington A, Kim J, Jimenez J, Bates D
ACS Synth Biol
. 2018 Oct;
7(11):2485-2496.
PMID: 30346148
The use of orthogonal ribosomes in combination with dynamic resource allocation controllers is a promising approach for relieving the negative effects of cellular resource limitations on the modularity of synthetic...
15.
Darlington A, Kim J, Jimenez J, Bates D
Nat Commun
. 2018 Feb;
9(1):695.
PMID: 29449554
Introduction of synthetic circuits into microbes creates competition between circuit and host genes for shared cellular resources, such as ribosomes. This can lead to the emergence of unwanted coupling between...
16.
Cavaliere M, Feng S, Soyer O, Jimenez J
Environ Microbiol
. 2017 Apr;
19(8):2949-2963.
PMID: 28447371
Microbial communities are increasingly utilized in biotechnology. Efficiency and productivity in many of these applications depends on the presence of cooperative interactions between members of the community. Two key processes...
17.
Qian Y, Huang H, Jimenez J, Del Vecchio D
ACS Synth Biol
. 2017 Mar;
6(7):1263-1272.
PMID: 28350160
A common approach to design genetic circuits is to compose gene expression cassettes together. While appealing, this modular approach is challenged by the fact that expression of each gene depends...
18.
Avendano R, Chaves N, Fuentes P, Sanchez E, Jimenez J, Chavarria M
Sci Rep
. 2016 Nov;
6:37155.
PMID: 27845437
Selenium (Se) is an essential element for the cell that has multiple applications in medicine and technology; microorganisms play an important role in Se transformations in the environment. Here we...
19.
Xulvi-Brunet R, Campbell G, Rajamani S, Jimenez J, Chen I
Methods
. 2016 May;
106:86-96.
PMID: 27211010
In vitro selection experiments in biochemistry allow for the discovery of novel molecules capable of specific desired biochemical functions. However, this is not the only benefit we can obtain from...
20.
Gyorgy A, Jimenez J, Yazbek J, Huang H, Chung H, Weiss R, et al.
Biophys J
. 2015 Aug;
109(3):639-46.
PMID: 26244745
Genetic circuits in living cells share transcriptional and translational resources that are available in limited amounts. This leads to unexpected couplings among seemingly unconnected modules, which result in poorly predictable...