Jose Florez
Overview
Explore the profile of Jose Florez including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
18
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Recent Articles
1.
Kennedy C, Doyle R, Gough O, Mcevoy C, Anallen S, McAnallen S, et al.
Kidney360
. 2024 Oct;
5(12):1799-1812.
PMID: 39450948
No abstract available.
2.
Hivert M, White F, Allard C, James K, Majid S, Aguet F, et al.
Res Sq
. 2023 Nov;
PMID: 37961187
Reduced insulin sensitivity (or greater insulin resistance) is a hallmark of normal physiology in late pregnancy and also underlies gestational diabetes mellitus (GDM) pathophysiology. We conducted transcriptomic profiling of 434...
3.
Manning A, Sevilla-Gonzalez M, Smith K, Wang N, Jensen A, Litkowski E, et al.
Res Sq
. 2023 Oct;
PMID: 37790568
Hyperinsulinemia is a complex and heterogeneous phenotype that characterizes molecular alterations that precede the development of type 2 diabetes (T2D). It results from a complex combination of molecular processes, including...
4.
Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes
Kwak S, Srinivasan S, Chen L, Todd J, Mercader J, Jensen E, et al.
Res Sq
. 2023 Jun;
PMID: 37292813
Youth-onset type 2 diabetes (T2D) is a growing public health concern. Its genetic basis and relationship to other forms of diabetes are largely unknown. To gain insight into the genetic...
5.
Schroeder P, Brenner L, Kaur V, Cromer S, Armstrong K, LaRocque R, et al.
Res Sq
. 2022 Jun;
PMID: 35677078
The high heterogeneity in the symptoms and severity of COVID-19 makes it challenging to identify high-risk patients early in the disease. Cardiometabolic comorbidities have shown strong associations with COVID-19 severity...
6.
Cefalu W, Verchere C, Rosenblum N, Andersen D, Arreaza-Rubin G, Dhara C, et al.
Diabetes
. 2021 Dec;
PMID: 34957490
One hundred years have passed since the discovery of insulin-an achievement that transformed diabetes from a fatal illness into a manageable chronic condition. The decades since that momentous achievement have...
7.
Alonso-Garcia V, Chaboya C, Li Q, Le B, Congleton T, Florez J, et al.
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33003435
For hundreds of indications, mesenchymal stromal cells (MSCs) have not achieved the expected therapeutic efficacy due to an inability of the cells to reach target tissues. We show that inducing...
8.
Ramsay A, Alonso-Garcia V, Chaboya C, Radut B, Le B, Florez J, et al.
Sci Rep
. 2019 Dec;
9(1):18480.
PMID: 31811211
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Ramsay A, Alonso-Garcia V, Chaboya C, Radut B, Le B, Florez J, et al.
Sci Rep
. 2019 Oct;
9(1):15395.
PMID: 31659216
Patients with Snyder-Robinson Syndrome (SRS) exhibit deficient Spermidine Synthase (SMS) gene expression, which causes neurodevelopmental defects and osteoporosis, often leading to extremely fragile bones. To determine the underlying mechanism for...
10.
Greka A, Gibson D, Mundel P, Demetri G, Hildebrandt F, Pollak M, et al.
Semin Nephrol
. 2016 Dec;
36(6):448.
PMID: 27987543
In the face of ever-increasing incidence and prevalence of kidney disease worldwide, the unmet need for new treatments is unprecedented. Precision medicine is defined as the use of modern technologies...