Jose C Nicolau
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Explore the profile of Jose C Nicolau including associated specialties, affiliations and a list of published articles.
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146
Citations
7654
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Recent Articles
1.
Nicolau J, Dalcoquio T, Giraldez R, Freitas F, Nicolau A, Furtado R, et al.
Int J Mol Sci
. 2025 Jan;
26(1.
PMID: 39796273
High-density lipoprotein (HDL) is associated with decreased incidence of cardiovascular events, and its functionality also influences prognosis. Exercise is an important tool to improve prognosis in the post-infarction (MI) population,...
2.
Mortality After Multivessel Revascularization in Patients With Diabetes and Acute Coronary Syndromes
Godoy L, Farkouh M, Austin P, Shah B, Qiu F, Sud M, et al.
JACC Adv
. 2024 Oct;
3(9):101203.
PMID: 39372470
Background: The optimal revascularization strategy in patients with diabetes and multivessel disease in the setting of a non-ST-segment elevation myocardial infarction (NSTEMI) is unknown. Objectives: The purpose of this study...
3.
Gibson C, Chi G, Duffy D, Bahit M, White H, Korjian S, et al.
J Am Coll Cardiol
. 2024 Sep;
84(22):2185-2192.
PMID: 39230545
Background: Following an acute myocardial infarction (AMI), patients remain at risk for subsequent cardiovascular (CV) events. In the AEGIS-II trial, CSL112, a human apolipoprotein A-I derived from plasma that enhances...
4.
Gibson C, Duffy D, Bahit M, Chi G, White H, Korjian S, et al.
Eur Heart J
. 2024 Sep;
45(47):5023-5038.
PMID: 39221651
Background And Aims: In the AEGIS-II trial (NCT03473223), CSL112, a human apolipoprotein A1 derived from plasma that increases cholesterol efflux capacity, did not significantly reduce the risk of the primary...
5.
Godoy L, Neal M, Goligher E, Cushman M, Houston B, Bradbury C, et al.
JACC Adv
. 2024 Jun;
3(3):100780.
PMID: 38938844
Background: Clinical trials suggest that therapeutic-dose heparin may prevent critical illness and vascular complications due to COVID-19, but knowledge gaps exist regarding the efficacy of therapeutic heparin including its comparative...
6.
Povsic T, Korjian S, Bahit M, Chi G, Duffy D, Alexander J, et al.
J Am Coll Cardiol
. 2024 Apr;
83(22):2163-2174.
PMID: 38588930
Background: The AEGIS-II trial hypothesized that CSL112, an intravenous formulation of human apoA-I, would lower the risk of plaque disruption, decreasing the risk of recurrent events such as myocardial infarction...
7.
Gibson C, Duffy D, Korjian S, Bahit M, Chi G, Alexander J, et al.
N Engl J Med
. 2024 Apr;
390(17):1560-1571.
PMID: 38587254
Background: Cardiovascular events frequently recur after acute myocardial infarction, and low cholesterol efflux - a process mediated by apolipoprotein A1, which is the main protein in high-density lipoprotein - has...
8.
Hess C, Hsia J, Carroll I, Nehler M, Ruf W, Morrow D, et al.
Arterioscler Thromb Vasc Biol
. 2023 Jun;
43(8):1572-1582.
PMID: 37381988
Background: Thrombo-inflammation is central to COVID-19-associated coagulopathy. TF (tissue factor), a driver of disordered coagulation and inflammation in viral infections, may be a therapeutic target in COVID-19. The safety and...
9.
Guimaraes P, Franken M, Tavares C, Silveira F, Antunes M, Bergo R, et al.
EuroIntervention
. 2023 Jun;
19(4):e323-e329.
PMID: 37306039
Dual antiplatelet therapy (DAPT) is currently the standard of care after percutaneous coronary intervention (PCI). Recent studies suggest that reducing DAPT to 1-3 months followed by an aspirin-free single antiplatelet...
10.
Chiang H, Aguiar M, Tavares B, Rosa V, Gomes S, Oliveira Jr M, et al.
J Am Soc Echocardiogr
. 2022 Dec;
36(5):504-513.
PMID: 36535625
Background: The diagnostic ultrasound-guided high mechanical index impulses during an intravenous microbubble infusion (sonothrombolysis) improve myocardial perfusion in acute ST segment elevation myocardial infarction, but its effect on left ventricular...