Jose C Machado
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Explore the profile of Jose C Machado including associated specialties, affiliations and a list of published articles.
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Articles
61
Citations
1608
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Recent Articles
1.
Off-The-Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Moura L, Malfanti A, Matos A, Peres C, Arminan A, Duro-Castano A, et al.
Adv Mater
. 2025 Feb;
:e2417348.
PMID: 39937158
Tumor-associated antigen-based cancer vaccines suffer from limited clinical success compared to alternative immunotherapies in melanoma, an aggressive skin cancer with an immunosuppressive tumor microenvironment. The anti-tumor potential of a multivalent...
2.
Pereira J, Arede L, Ferreira F, Matos A, Pereira D, Santos R, et al.
Leukemia
. 2024 Oct;
39(1):178-188.
PMID: 39455852
Despite advancements in cancer immunotherapy, most lymphomas remain unresponsive to checkpoint inhibitors. P-selectin glycoprotein ligand-1 (PSGL-1), recently identified as a promoter of T-cell exhaustion in murine melanoma models, has emerged...
3.
Batista I, Machado J, Melo S
Trends Cancer
. 2024 Aug;
10(10):947-968.
PMID: 39168775
Exosomes are regarded as having transformative potential for clinical applications. Exosome-based liquid biopsies offer a noninvasive method for early cancer detection and real-time disease monitoring. Clinical trials are underway to...
4.
Adem B, Bastos N, Ruivo C, Sousa-Alves S, Dias C, Vieira P, et al.
Nat Commun
. 2024 Feb;
15(1):1496.
PMID: 38383468
Pancreatic ductal adenocarcinoma (PDAC), a lethal disease, requires a grasp of its biology for effective therapies. Exosomes, implicated in cancer, are poorly understood in living systems. Here we use the...
5.
Pereira M, Ribeiro C, Ferreira G, Machado J, Leite A
Health Psychol Rep
. 2023 Dec;
10(1):47-57.
PMID: 38084367
Background: This study assessed the indirect effect of body image in the relationship between illness duration, optimism, coping strategies and psychological distress as well as the moderator role of being...
6.
Bujanda L, Nyssen O, Ramos J, Bordin D, Tepes B, Perez-Aisa A, et al.
Am J Gastroenterol
. 2023 Nov;
119(4):646-654.
PMID: 37983769
Introduction: Antibiotic resistance is one of the main factors that determine the efficacy of treatments to eradicate Helicobacter pylori infection. Our aim was to evaluate the effectiveness of first-line and...
7.
Bastos N, Castaldo S, Adem B, Machado J, Melo C, Melo S
J Transl Med
. 2023 Aug;
21(1):578.
PMID: 37641131
Background: Pancreatic ductal adenocarcinoma (PDAC) is expected to soon surpass colorectal cancer as a leading cause of cancer mortality in both males and females in the US, only lagging behind...
8.
Pereira-Marques J, Ferreira R, Machado J, Figueiredo C
Best Pract Res Clin Gastroenterol
. 2021 May;
50-51:101734.
PMID: 33975676
Colonization of the stomach by Helicobacter pylori is the trigger for a series of gastric mucosal changes that culminate in gastric cancer. Infection with this bacterium is considered the major...
9.
C Silva M, Fernandes A, Oliveira M, Resende C, Correia A, de-Freitas-Junior J, et al.
Cancer Immunol Res
. 2020 Sep;
8(11):1407-1425.
PMID: 32933968
Tumor growth is accompanied with dramatic changes in the cellular glycome, such as the aberrant expression of complex branched N-glycans. However, the role of this protumoral N-glycan in immune evasion...
10.
Gullo I, Costa C, Silva S, Ferreira C, Motta A, P Silva S, et al.
Cells
. 2020 Jun;
9(6).
PMID: 32575504
Gastric carcinoma (GC) represents the most common cause of death in patients with common variable immunodeficiency (CVID). However, a limited number of cases have been characterised so far. In this...