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Jorng-Tzong Horng

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Articles 83
Citations 1247
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Recent Articles
1.
Yao L, Guan J, Xie P, Chung C, Zhao Z, Dong D, et al.
Nucleic Acids Res . 2024 Nov; 53(D1):D364-D376. PMID: 39540425
Antimicrobial resistance is one of the most urgent global health threats, especially in the post-pandemic era. Antimicrobial peptides (AMPs) offer a promising alternative to traditional antibiotics, driving growing interest in...
2.
Chung C, Tang Y, Chiu Y, Li S, Hsieh W, Yao L, et al.
Nucleic Acids Res . 2024 Nov; 53(D1):D377-D386. PMID: 39526378
Post-translational modifications (PTMs) are essential for modulating protein function and influencing stability, activity and signaling processes. The dbPTM 2025 update significantly expands the database to include over 2.79 million PTM...
3.
Chung C, Chien C, Tang Y, Wu L, Hsu J, Lu J, et al.
iScience . 2024 Sep; 27(9):110718. PMID: 39262770
The rise of antibiotic resistance necessitates effective alternative therapies. Antimicrobial peptides (AMPs) are promising due to their broad inhibitory effects. This study focuses on predicting the minimum inhibitory concentration (MIC)...
4.
Chung C, Liou J, Wu L, Horng J, Lee T
iScience . 2023 Nov; 26(12):108250. PMID: 38025779
The challenge of drug-resistant bacteria to global public health has led to increased attention on antimicrobial peptides (AMPs) as a targeted therapeutic alternative with a lower risk of resistance. However,...
5.
Wang Z, Pang Y, Chung C, Wang H, Cui H, Chiang Y, et al.
Brief Bioinform . 2023 Sep; 24(6). PMID: 37742050
The emergence of multidrug-resistant bacteria is a critical global crisis that poses a serious threat to public health, particularly with the rise of multidrug-resistant Staphylococcus aureus. Accurate assessment of drug...
6.
Chung C, Wang H, Yao C, Wu L, Lu J, Horng J, et al.
Microbiol Spectr . 2023 Apr; 11(3):e0347922. PMID: 37042778
In clinical microbiology, matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) is frequently employed for rapid microbial identification. However, rapid identification of antimicrobial resistance (AMR) in Escherichia coli based on...
7.
Chung C, Wang H, Chou P, Wu L, Lu J, Horng J, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674514
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) has been used to identify microorganisms and predict antibiotic resistance. The preprocessing method for the MS spectrum is key to extracting critical...
8.
Wang H, Hsieh T, Chung C, Chang H, Horng J, Lu J, et al.
Front Microbiol . 2022 Jun; 13:821233. PMID: 35756017
Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) has recently become a useful analytical approach for microbial identification. The presence and absence of specific peaks on MS spectra are...
9.
Zhang J, Wang Z, Wang H, Chung C, Horng J, Lu J, et al.
Front Microbiol . 2022 May; 13:853775. PMID: 35495667
Multidrug resistance has become a phenotype that commonly exists among and is a serious concern for infection treatment. Nowadays, to detect the antibiotic susceptibility, antibiotic testing is generated based on...
10.
Wang C, Wang Z, Wang H, Chung C, Horng J, Lu J, et al.
Front Microbiol . 2022 Mar; 13:827451. PMID: 35356528
is one of the most common causes of hospital- and community-acquired pneumoniae. Resistance to the extensively used quinolone antibiotic, such as ciprofloxacin, has increased in , which leads to the...