Jorida Coku
Overview
Explore the profile of Jorida Coku including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
328
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Coku J, Booth D, Skoda J, Pedrotty M, Vogel J, Liu K, et al.
EMBO J
. 2022 Feb;
41(8):e108272.
PMID: 35211994
Most cancer deaths result from progression of therapy resistant disease, yet our understanding of this phenotype is limited. Cancer therapies generate stress signals that act upon mitochondria to initiate apoptosis....
2.
Shen Y, Alvarez M, Bisikirska B, Lachmann A, Realubit R, Pampou S, et al.
PLoS Comput Biol
. 2017 Oct;
13(10):e1005599.
PMID: 29023443
A large fraction of the proteins that are being identified as key tumor dependencies represent poor pharmacological targets or lack clinically-relevant small-molecule inhibitors. Availability of fully generalizable approaches for the...
3.
Kurt Y, Coku J, Akman H, Naini A, Lu J, Engelstad K, et al.
Child Neurol Open
. 2017 May;
3:2329048X15627937.
PMID: 28503604
Dystonia is often associated with the symmetrical basal ganglia lesions of Leigh syndrome. However, it has also been associated with mitochondrial mutations, with or without Leber hereditary optic neuropathy. The...
4.
Akman H, Kakhlon O, Coku J, Peverelli L, Rosenmann H, Rozenstein-Tsalkovich L, et al.
JAMA Neurol
. 2015 Feb;
72(4):441-5.
PMID: 25665141
Importance: We describe a deep intronic mutation in adult polyglucosan body disease. Similar mechanisms can also explain manifesting heterozygous cases in other inborn metabolic diseases. Objective: To explain the genetic...
5.
Emmanuele V, Garcia-Cazorla A, Huang H, Coku J, Dorado B, Cortes E, et al.
J Neurol Sci
. 2012 Apr;
317(1-2):29-34.
PMID: 22483853
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a maternally inherited mitochondrial syndrome characterized by seizures, migrainous headaches, lactic acidosis, vomiting, and recurrent stroke-like episodes. Patients often suffer from...
6.
Quinzii C, Lopez L, Gilkerson R, Dorado B, Coku J, Naini A, et al.
FASEB J
. 2010 May;
24(10):3733-43.
PMID: 20495179
Coenzyme Q(10) (CoQ(10)) is essential for electron transport in the mitochondrial respiratory chain and antioxidant defense. The relative importance of respiratory chain defects, ROS production, and apoptosis in the pathogenesis...
7.
Berardo A, Coku J, Kurt B, DiMauro S, Hirano M
Neuromuscul Disord
. 2010 Feb;
20(3):204-6.
PMID: 20149659
We describe a 62-year-old woman with chronic progressive external ophthalmoplegia (CPEO), multiple lipomas, diabetes mellitus, and a novel mitochondrial DNA (mtDNA) mutation at nucleotide 4302 (4302A>G) of the tRNA(Ile) gene...
8.
Nishigaki Y, Ueno H, Coku J, Koga Y, Fujii T, Sahashi K, et al.
Mitochondrion
. 2010 Jan;
10(3):300-8.
PMID: 20064630
We established an extensive and rapid system using suspension array to detect 61 representative mitochondrial DNA (mtDNA) heteroplasmic or homoplasmic point mutations (29 for Series A and 32 for Series...
9.
Coku J, Shanske S, Mehrazin M, Tanji K, Naini A, Emmanuele V, et al.
J Neurol Sci
. 2009 Dec;
290(1-2):166-8.
PMID: 20022607
Pathogenic mutations in the tRNA(Leu(UCN)) gene of mitochondrial DNA (mtDNA) have been invariably accompanied by skeletal myopathy with or without chronic progressive external ophthalmoplegia (CPEO). We report a young woman...
10.
Horvath R, Kemp J, Tuppen H, Hudson G, Oldfors A, Marie S, et al.
Brain
. 2009 Sep;
132(Pt 11):3165-74.
PMID: 19720722
Childhood-onset mitochondrial encephalomyopathies are usually severe, relentlessly progressive conditions that have a fatal outcome. However, a puzzling infantile disorder, long known as 'benign cytochrome c oxidase deficiency myopathy' is an...