Jorgen S Petersen
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Explore the profile of Jorgen S Petersen including associated specialties, affiliations and a list of published articles.
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18
Citations
316
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Recent Articles
1.
Possenti R, Muccioli G, Petrocchi P, Cero C, Cabassi A, Vulchanova L, et al.
Biochem J
. 2011 Sep;
441(1):511-22.
PMID: 21880012
The peptides encoded by the VGF gene are gaining biomedical interest and are increasingly being scrutinized as biomarkers for human disease. An endocrine/neuromodulatory role for VGF peptides has been suggested...
2.
Neerup T, Stahlhut M, Petersen J, Daugaard J, Jensen J, Peng Z, et al.
Bone
. 2011 Mar;
48(6):1319-27.
PMID: 21376152
Daily injections of human parathyroid hormone (1-34), hPTH(1-34), provide a highly effective treatment option for severe osteoporosis. However, PTH analogs shorter than 28 amino acids do not retain any bone...
3.
Axelsen L, Lademann J, Petersen J, Holstein-Rathlou N, Ploug T, Prats C, et al.
Am J Physiol Regul Integr Comp Physiol
. 2010 Apr;
298(6):R1560-70.
PMID: 20357025
Metabolic syndrome and obesity-related diseases are affecting more and more people in the Western world. The basis for an effective treatment of these patients is a better understanding of the...
4.
Axelsen L, Pedersen H, Petersen J, Holstein-Rathlou N, Kjolbye A
J Pharmacol Toxicol Methods
. 2010 Feb;
61(3):292-6.
PMID: 20172035
Introduction: High cholesterol-fructose (HCF) fed rats have previously been described as an animal model of impaired cardiac insulin signaling and decreased contractile performance. In this study, we evaluated the metabolic...
5.
Hennan J, Swillo R, Morgan G, Rossman E, Kantrowitz J, Butera J, et al.
J Cardiovasc Pharmacol Ther
. 2009 Sep;
14(3):207-14.
PMID: 19721133
The antiarrhythmic dipeptide, GAP-134, ([2S,4R]-1[2-aminoacetyl]-4-benzamido-pyrrolidine-2-carboxylic acid) was evaluated in canine ischemia/reperfusion model. In dogs subjected to 60-minute ischemia and 4-hour reperfusion, GAP-134 was administered 10 minutes before reperfusion as a...
6.
Easton J, Petersen J, Martin P
Naunyn Schmiedebergs Arch Pharmacol
. 2009 Mar;
380(1):11-24.
PMID: 19326099
The anti-arrhythmic peptide AAP10 has previously been shown to acutely upregulate electrical cell-to-cell coupling mediated via connexin 43 gap junctions. In the present work, we have further examined the connexin...
7.
Rossman E, Liu K, Morgan G, Swillo R, Krueger J, Gardell S, et al.
J Pharmacol Exp Ther
. 2009 Mar;
329(3):1127-33.
PMID: 19252062
Gap junction uncoupling can alter conduction pathways and promote cardiac re-entry mechanisms that potentiate many supraventricular arrhythmias, such as atrial fibrillation (AF) and atrial flutter (AFL). Our objective was to...
8.
Butera J, Larsen B, Hennan J, Kerns E, Di L, Alimardanov A, et al.
J Med Chem
. 2009 Jan;
52(4):908-11.
PMID: 19175320
Rotigaptide (3) is an antiarrhythmic peptide that improves cardiac conduction by modifying gap-junction communication. Small molecule gap-junction modifiers with improved physical properties were identified from a Zealand Pharma peptide library...
9.
Fischetti C, Rizzi A, Gavioli E, Marzola G, Trapella C, Guerrini R, et al.
Peptides
. 2008 Nov;
30(2):248-55.
PMID: 18992780
ZP120 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) ligand. In previous studies, the effects of ZP120 were found to be sensitive to J-113397 in mouse tissues while resistant to...
10.
Lin X, Zemlin C, Hennan J, Petersen J, Veenstra R
Cardiovasc Res
. 2008 Apr;
79(3):416-26.
PMID: 18430749
Aims: Rotigaptide is proposed to exert its anti-arrhythmic effects by improving myocardial gap-junction communication. To directly investigate the mechanisms of rotigaptide action, we treated cultured neonatal murine ventricular cardiomyocytes with...