Jorge Galino
Overview
Explore the profile of Jorge Galino including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
659
Followers
0
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Recent Articles
1.
Abad-Montero D, Gandioso A, Izquierdo-Garcia E, Chumillas S, Rovira A, Bosch M, et al.
J Am Chem Soc
. 2025 Feb;
147(9):7360-7376.
PMID: 39953993
Hypoxia, a hallmark of many solid tumors, is linked to increased cancer aggressiveness, metastasis, and resistance to conventional therapies, leading to poor patient outcomes. This challenges the efficiency of photodynamic...
2.
Hayes M, Naik A, Mora L, Inarra B, Ibarruri J, Bald C, et al.
Mar Drugs
. 2024 Jul;
22(7).
PMID: 39057406
This study generated bioactive hydrolysates using the enzyme Alcalase and autolysis from mesopelagic fish, including and . Generated hydrolysates were investigated for their bioactivities using in vitro bioassays, and bioactive...
3.
Ranea-Robles P, Galino J, Espinosa L, Schluter A, Ruiz M, Calingasan N, et al.
Neuropathol Appl Neurobiol
. 2021 Jul;
48(1):e12747.
PMID: 34237158
Aims: Mitochondrial dysfunction and inflammation are at the core of axonal degeneration in several multifactorial neurodegenerative diseases, including multiple sclerosis, Alzheimer's disease, and Parkinson's disease. The transcriptional coregulator RIP140/NRIP1 (receptor-interacting...
4.
Cervellini I, Galino J, Zhu N, Fricker F, Bao L, Bennett D
Glia
. 2019 Jul;
67(10):1990-2000.
PMID: 31339187
Membrane metallo-endopeptidase (MME), also known as neprilysin (NEP), has been of interest for its role in neurodegeneration and pain due to its ability to degrade β-amyloid and substance-P, respectively. In...
5.
Galino J, Cervellini I, Zhu N, Stoberl N, Hutte M, Fricker F, et al.
J Cell Biol
. 2019 Jun;
218(7):2370-2387.
PMID: 31201266
RalA and RalB are small GTPases that are involved in cell migration and membrane dynamics. We used transgenic mice in which one or both GTPases were genetically ablated to investigate...
6.
Bartus K, Burnside E, Galino J, James N, Bennett D, Bradbury E
Glia
. 2019 Jan;
67(6):1036-1046.
PMID: 30637799
We recently discovered a novel role for neuregulin-1 (Nrg1) signaling in mediating spontaneous regenerative processes and functional repair after spinal cord injury (SCI). We revealed that Nrg1 is the molecular...
7.
Dawes J, Weir G, Middleton S, Patel R, Chisholm K, Pettingill P, et al.
Neuron
. 2018 Feb;
97(4):806-822.e10.
PMID: 29429934
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized....
8.
Cervellini I, Galino J, Zhu N, Allen S, Birchmeier C, Bennett D
J Neurosci
. 2017 Dec;
38(3):679-690.
PMID: 29217688
The MAPK/ERK pathway has a critical role in PNS development. It is required for Schwann cell (SC) differentiation and myelination; sustained embryonic MAPK/ERK activation in SCs enhances myelin growth overcoming...
9.
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination
Clark A, Kaller M, Galino J, Willison H, Rinaldi S, Bennett D
Brain
. 2017 Mar;
140(4):898-913.
PMID: 28334857
See Saporta and Shy (doi:10.1093/awx048) for a scientific commentary on this article.Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve...
10.
Bartus K, Galino J, James N, Hernandez-Miranda L, Dawes J, Fricker F, et al.
Brain
. 2016 Mar;
139(Pt 5):1394-416.
PMID: 26993800
Following traumatic spinal cord injury, acute demyelination of spinal axons is followed by a period of spontaneous remyelination. However, this endogenous repair response is suboptimal and may account for the...