Jorge D Da Silva
Overview
Explore the profile of Jorge D Da Silva including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
83
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0
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Recent Articles
1.
Kleinendorst L, Abawi O, Vos N, van der Valk E, Maas S, Morgan A, et al.
Clin Obes
. 2024 Apr;
14(4):e12661.
PMID: 38596856
Most patients with GNB1 encephalopathy have developmental delay and/or intellectual disability, brain anomalies and seizures. Recently, two cases with GNB1 encephalopathy caused by haploinsufficiency have been reported that also show...
2.
Antunes C, Da Silva J, Guerra-Gomes S, Alves N, Loureiro-Campos E, Pinto L, et al.
Mol Neurobiol
. 2022 Jun;
59(8):4892-4901.
PMID: 35665901
TET enzymes (TET1-3) are dioxygenases that oxidize 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and are involved in the DNA demethylation process. In line with the observed 5hmC abundance in the brain,...
3.
Antunes C, Da Silva J, Guerra-Gomes S, Alves N, Ferreira F, Loureiro-Campos E, et al.
Mol Psychiatry
. 2020 Feb;
26(5):1445-1457.
PMID: 32103150
TET3 is a member of the ten-eleven translocation (TET) family of enzymes which oxidize 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). Tet3 is highly expressed in the brain, where 5hmC levels are...
4.
Mendes-Pinheiro B, Anjo S, Manadas B, Da Silva J, Marote A, Behie L, et al.
Front Bioeng Biotechnol
. 2019 Nov;
7:294.
PMID: 31737616
Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in the human midbrain causing motor dysfunctions. The exact mechanism behind dopaminergic cell death is still not...