C Joana Marques
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Explore the profile of C Joana Marques including associated specialties, affiliations and a list of published articles.
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20
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1364
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Recent Articles
1.
Canicais C, Sobral D, Vasconcelos S, Cunha M, Pinto A, Mesquita Guimaraes J, et al.
Dev Biol
. 2024 Dec;
519():55-64.
PMID: 39681207
Human oocytes are highly specialized cells with the capacity to store and regulate mRNAs during oocyte maturation, in preparation for post-fertilization steps. Here we performed single-oocyte transcriptomic analysis of human...
2.
Camilo V, Pacheco M, Moreira-Silva F, Outeiro-Pinho G, Gaspar V, Mano J, et al.
Biomolecules
. 2023 Oct;
13(10).
PMID: 37892208
The androgens/androgen receptor (AR) axis is the main therapeutic target in prostate cancer (PCa). However, while initially responsive, a subset of tumors loses AR expression through mechanisms putatively associated with...
3.
Vasconcelos S, Canicais C, Chuva de Sousa Lopes S, Marques C, Doria S
Clin Epigenetics
. 2023 Apr;
15(1):66.
PMID: 37095555
The placenta is a temporary organ that is essential for supporting mammalian embryo and fetal development. Understanding the molecular mechanisms underlying trophoblast differentiation and placental function may contribute to improving...
4.
Antunes C, Da Silva J, Guerra-Gomes S, Alves N, Loureiro-Campos E, Pinto L, et al.
Mol Neurobiol
. 2022 Jun;
59(8):4892-4901.
PMID: 35665901
TET enzymes (TET1-3) are dioxygenases that oxidize 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and are involved in the DNA demethylation process. In line with the observed 5hmC abundance in the brain,...
5.
Nagirnaja L, Morup N, Nielsen J, Stakaitis R, Golubickaite I, Oud M, et al.
N Engl J Med
. 2021 Aug;
385(8):707-719.
PMID: 34347949
Background: P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are short (21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ cells, where they regulate aberrant expression...
6.
Canicais C, Vasconcelos S, Ramalho C, Marques C, Doria S
J Assist Reprod Genet
. 2021 Jan;
38(4):791-801.
PMID: 33389447
Purpose: Intrauterine growth restriction (IUGR) is a fetal growth complication that can be caused by ineffective nutrient transfer from the mother to the fetus via the placenta. Abnormal placental development...
7.
Montibus B, Cercy J, Bouschet T, Charras A, Maupetit-Mehouas S, Nury D, et al.
Cell Mol Life Sci
. 2020 May;
78(2):757-768.
PMID: 32405722
The acquisition of cell identity is associated with developmentally regulated changes in the cellular histone methylation signatures. For instance, commitment to neural differentiation relies on the tightly controlled gain or...
8.
Carvalho B, Marques C, Santos-Silva R, Fontoura M, Carvalho D, Carvalho F
Exp Clin Endocrinol Diabetes
. 2020 Mar;
129(7):477-481.
PMID: 32131114
Congenital Adrenal Hyperplasia is a group of genetic autosomal recessive disorders that affects adrenal steroidogenesis in the adrenal cortex. One of the most common defects associated with Congenital Adrenal Hyperplasia...
9.
Antunes C, Da Silva J, Guerra-Gomes S, Alves N, Ferreira F, Loureiro-Campos E, et al.
Mol Psychiatry
. 2020 Feb;
26(5):1445-1457.
PMID: 32103150
TET3 is a member of the ten-eleven translocation (TET) family of enzymes which oxidize 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC). Tet3 is highly expressed in the brain, where 5hmC levels are...
10.
Santiago M, Antunes C, Guedes M, Iacovino M, Kyba M, Reik W, et al.
Cell Mol Life Sci
. 2020 Jan;
77(14):2885.
PMID: 31919574
The article Tet3 regulates cellular identity and DNA methylation in neural progenitor cells, written by Miguel R. Branco and C. Joana Marques, was originally published electronically on the publisher's internet...