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Jordi Serrat

Explore the profile of Jordi Serrat including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Gracia J, Buil M, Castro J, Eichhorn P, Ferrer M, Gavalda A, et al.
J Med Chem . 2016 Dec; 59(23):10479-10497. PMID: 27933955
Cyclic nucleotide cAMP is a ubiquitous secondary messenger involved in a plethora of cellular responses to biological agents involving activation of adenylyl cyclase. Its intracellular levels are tightly controlled by...
2.
Taltavull J, Serrat J, Gracia J, Gavalda A, Cordoba M, Calama E, et al.
Eur J Med Chem . 2011 Aug; 46(10):4946-56. PMID: 21871695
A series of pyrido[3',2':4,5]furo[3,2-d]pyrimidines (PFP) were synthesized and tested for phosphodiesterase type 4 (PDE4) inhibitory activity, with the potential to treat asthma and chronic obstructive pulmonary disease (COPD). Structure-activity relationships...
3.
Taltavull J, Serrat J, Gracia J, Gavalda A, Andres M, Cordoba M, et al.
J Med Chem . 2010 Sep; 53(19):6912-22. PMID: 20825218
A series of pyrido[3',2':4,5]thieno[3,2-d]pyrimidines (PTP) has been synthesized and tested as phosphodiesterase IV inhibitors (PDE4), a target for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Structure-activity relationships...
4.
Serrat J, Roza J, Planella T
Anesth Analg . 2004 Nov; 99(6):1803-1804. PMID: 15562075
The frequency of hepatic hydrothorax in cirrhotic patients is reported to be approximately 5%. The pleural effusion is predominantly right-sided (85% of cases) but may be bilateral. Although most often...