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Jordan R Yaron

Explore the profile of Jordan R Yaron including associated specialties, affiliations and a list of published articles. Areas
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Articles 53
Citations 416
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Recent Articles
1.
Yaron J, Pallod S, Grigaitis-Esman N, Singh V, Rhodes S, Patel D, et al.
Biomaterials . 2024 Nov; 315:122967. PMID: 39586217
Tissue repair is a highly regulated process involving immune, stromal, vascular, and parenchymal cell responses. Mediators of cellular responses at different phases of the healing process stimulate transitions through the...
2.
Pallod S, Aguilera Olvera R, Ghosh D, Rai L, Brimo S, DeCambra W, et al.
Biomaterials . 2024 Jun; 311:122668. PMID: 38908232
Conventional wound approximation devices, including sutures, staples, and glues, are widely used but risk of wound dehiscence, local infection, and scarring can be exacerbated in these approaches, including in diabetic...
3.
Yaron J, Gosangi M, Pallod S, Rege K
Bioeng Transl Med . 2024 May; 9(3):e10637. PMID: 38818119
Dermal wounds are a major global health burden made worse by common comorbidities such as diabetes and infection. Appropriate wound closure relies on a highly coordinated series of cellular events,...
4.
Yaron J, Bakkaloglu S, Grigaitis N, Babur F, Macko S, Rhodes S, et al.
Front Immunol . 2024 Mar; 15:1340405. PMID: 38426101
The inflammasome is a multiprotein complex critical for the innate immune response to injury. Inflammasome activation initiates healthy wound healing, but comorbidities with poor healing, including diabetes, exhibit pathologic, sustained...
5.
Ghosh D, Yaron J, Abedin M, Godeshala S, Kumar S, Kilbourne J, et al.
Biomaterials . 2024 Feb; 306:122496. PMID: 38373363
Slow-healing and chronic wounds represent a major global economic and medical burden, and there is significant unmet need for novel therapies which act to both accelerate wound closure and enhance...
6.
Inamdar S, Suresh A, Mangal J, Ng N, Sundem A, Wu C, et al.
Nat Commun . 2023 Sep; 14(1):5333. PMID: 37660049
Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is challenging. Herein, a strategy is presented where glycolysis is inhibited...
7.
Inamdar S, Suresh A, Mangal J, Ng N, Sundem A, Shokrollahzadeh Behbahani H, et al.
Biomaterials . 2023 Aug; 301:122292. PMID: 37643489
Succinate is an important metabolite that modulates metabolism of immune cells and cancer cells in the tumor microenvironment (TME). Herein, we report that polyethylene succinate (PES) microparticles (MPs) biomaterial mediated...
8.
Inamdar S, Suresh A, Mangal J, Ng N, Sundem A, Shokrollahzadeh Behbahani H, et al.
J Control Release . 2023 May; 358:541-554. PMID: 37182805
Boosting the metabolism of immune cells while restricting cancer cell metabolism is challenging. Herein, we report that using biomaterials for the controlled delivery of succinate metabolite to phagocytic immune cells...
9.
Jaggarapu M, Ghosh D, Johnston T, Yaron J, Mangal J, Inamdar S, et al.
J Biomed Mater Res A . 2023 Mar; 111(9):1372-1378. PMID: 36951217
Metabolites are not only involved in energy pathways but can also act as signaling molecules. Herein, we demonstrate that polyesters of alpha-ketoglutararte (paKG) can be generated by reacting aKG with...
10.
Ghosh D, Salinas C, Pallod S, Roberts J, Makin I, Yaron J, et al.
Bioeng Transl Med . 2023 Mar; 8(2):e10412. PMID: 36925709
Injuries caused by surgical incisions or traumatic lacerations compromise the structural and functional integrity of skin. Immediate approximation and robust repair of skin are critical to minimize occurrences of dehiscence...