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Joram M Posma

Explore the profile of Joram M Posma including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 1278
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Recent Articles
1.
Rocha Liedl E, Yassin S, Kasapi M, Posma J
Comput Struct Biotechnol J . 2024 Dec; 23:4108-4123. PMID: 39624167
Cancer is the second leading cause of disease-related death worldwide, and machine learning-based identification of novel biomarkers is crucial for improving early detection and treatment of various cancers. A key...
2.
Wang M, Vijayaraghavan A, Beck T, Posma J
J Proteome Res . 2024 May; 23(6):1915-1925. PMID: 38733346
Enzymes are indispensable in many biological processes, and with biomedical literature growing exponentially, effective literature review becomes increasingly challenging. Natural language processing methods offer solutions to streamline this process. This...
3.
Eriksen R, White M, Dawed A, Perez I, Posma J, Haid M, et al.
J Clin Endocrinol Metab . 2024 Apr; 109(9):e1697-e1707. PMID: 38686701
Context: The role of glucagon-like peptide-1 (GLP-1) in type 2 diabetes (T2D) and obesity is not fully understood. Objective: We investigate the association of cardiometabolic, diet, and lifestyle parameters on...
4.
Kasapi M, Xu K, Ebbels T, ORegan D, Ware J, Posma J
Bioinformatics . 2024 Feb; 40(3). PMID: 38383048
Motivation: Random forests (RFs) can deal with a large number of variables, achieve reasonable prediction scores, and yield highly interpretable feature importance values. As such, RFs are appropriate models for...
5.
Boubnovski Martell M, Linton-Reid K, Hindocha S, Chen M, Moreno P, Alvarez-Benito M, et al.
NPJ Precis Oncol . 2024 Feb; 8(1):28. PMID: 38310164
The rich chemical information from tissue metabolomics provides a powerful means to elaborate tissue physiology or tumor characteristics at cellular and tumor microenvironment levels. However, the process of obtaining such...
6.
Rundle M, Fiamoncini J, Thomas E, Wopereis S, Afman L, Brennan L, et al.
Am J Clin Nutr . 2023 Sep; 118(3):591-604. PMID: 37661105
Background: The capacity of an individual to respond to changes in food intake so that postprandial metabolic perturbations are resolved, and metabolism returns to its pre-prandial state, is called phenotypic...
7.
Alexander J, Posma J, Scott A, Poynter L, Mason S, Doria M, et al.
Microbiome . 2023 May; 11(1):100. PMID: 37158960
Background And Aims: The gut microbiota is implicated in the pathogenesis of colorectal cancer (CRC). We aimed to map the CRC mucosal microbiota and metabolome and define the influence of...
8.
Garcia-Perez I, Posma J, Chambers E, Mathers J, Draper J, Beckmann M, et al.
Nat Food . 2023 May; 1(6):355-364. PMID: 37128097
Habitual consumption of poor quality diets is linked directly to risk factors for many non-communicable diseases. This has resulted in the vast majority of countries and the World Health Organization...
9.
Posma J, Garcia-Perez I, Frost G, Aljuraiban G, Chan Q, Van Horn L, et al.
Nat Food . 2023 Apr; 2(7):541-542. PMID: 37117689
No abstract available.
10.
Penney N, Yeung D, Garcia-Perez I, Posma J, Kopytek A, Garratt B, et al.
Commun Med (Lond) . 2022 Oct; 2:127. PMID: 36217535
Background: Resolution of type 2 diabetes (T2D) is common following bariatric surgery, particularly Roux-en-Y gastric bypass. However, the underlying mechanisms have not been fully elucidated. Methods: To address this we...