Joram M Mwacharo
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Explore the profile of Joram M Mwacharo including associated specialties, affiliations and a list of published articles.
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77
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919
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Recent Articles
1.
Shi X, Ma C, Chen N, Xu M, Kambal S, Cai Z, et al.
Mol Biol Evol
. 2025 Feb;
42(2).
PMID: 39921600
Mitochondrial function relies on the coordinated interactions between genes in the mitochondrial DNA and nuclear genomes. Imperfect interactions following mitonuclear incompatibility may lead to reduced fitness. Mitochondrial DNA introgressions across...
2.
Bian P, Li J, Zhou S, Wang X, Gong M, Guo X, et al.
Mol Biol Evol
. 2024 Dec;
41(12).
PMID: 39665690
Pangenomes can facilitate a deeper understanding of genome complexity. Using de novo phased long-read assemblies of eight representative goat breeds, we constructed a graph-based pangenome of goats (Capra hircus) and...
3.
Ben-Jemaa S, Yahyaoui G, Kdidi S, Najjari A, Lenstra J, Mastrangelo S, et al.
Anim Genet
. 2024 Nov;
56(1):e13487.
PMID: 39573836
North Africa counts several sheep breeds that can be categorized as fat- and thin-tailed. The former are well adapted to dryland environments. In this study, we used 50K genome-wide single...
4.
Da Silva A, Ahbara A, Baazaoui I, Jemaa S, Cao Y, Ciani E, et al.
Anim Genet
. 2024 Nov;
56(1):e13488.
PMID: 39561986
Domesticated sheep have adapted to contrasting and extreme environments and continue to play important roles in local community-based economies throughout Africa. Here we review the Neolithic migrations of thin-tailed sheep...
5.
He M, Lv X, Mwacharo J, Li Y, Wang S, Sun W
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39063192
Wool is generated by hair follicles (HFs), which are crucial in defining the length, diameter, and morphology of wool fibers. However, the regulatory mechanism of HF growth and development remains...
6.
Belay S, Belay G, Nigussie H, Ahbara A, Tijjani A, Dessie T, et al.
Sci Rep
. 2024 Jun;
14(1):14908.
PMID: 38942813
Anthropological and biophysical processes have shaped livestock genomes over Millenia and can explain their current geographic distribution and genetic divergence. We analyzed 57 Ethiopian indigenous domestic goat genomes alongside 67...
7.
Lv X, He M, Wang S, Zheng W, Zhou H, Mwacharo J, et al.
Animals (Basel)
. 2024 Jun;
14(11).
PMID: 38891747
Previous studies have shown that the gene is differentially expressed in Hu sheep lamb skin of different pattern types, and its expression level is significantly correlated with hair follicle indices...
8.
Sheriff O, Ahbara A, Haile A, Alemayehu K, Han J, Mwacharo J
Front Genet
. 2024 Jun;
15:1353026.
PMID: 38854428
Ethiopia has about 52 million indigenous goats with marked phenotypic variability, which is the outcome of natural and artificial selection. Here, we obtained whole-genome sequence data of three Ethiopian indigenous...
9.
Xu Y, Chen W, Yang H, Song Z, Wang Y, Su R, et al.
Vet Sci
. 2024 May;
11(5).
PMID: 38787178
Diarrhea is the most common issue in sheep farms, typically due to pathogenic () infections, such as F17. microRNA, a primary type of non-coding RNA, has been shown to be...
10.
Belay S, Belay G, Nigussie H, Jian-Lin H, Tijjani A, Ahbara A, et al.
Sci Data
. 2024 Jan;
11(1):139.
PMID: 38287052
Domestic goats are distributed worldwide, with approximately 35% of the one billion world goat population occurring in Africa. Ethiopia has 52.5 million goats, ~99.9% of which are considered indigenous landraces...