Joon-Hyuk Lee
Overview
Explore the profile of Joon-Hyuk Lee including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
649
Followers
0
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Recent Articles
1.
Kadowaki A, Wheeler M, Li Z, Andersen B, Lee H, Illouz T, et al.
Nat Neurosci
. 2025 Mar;
28(3):470-486.
PMID: 40033124
Astrocytes promote neuroinflammation and neurodegeneration in multiple sclerosis (MS) through cell-intrinsic activities and their ability to recruit and activate other cell types. In a genome-wide CRISPR-based forward genetic screen investigating...
2.
Izzy S, Yahya T, Albastaki O, Abou-El-Hassan H, Aronchik M, Cao T, et al.
Nat Neurosci
. 2025 Feb;
28(3):499-516.
PMID: 40016353
Neuroinflammation plays a crucial role in traumatic brain injury (TBI), contributing to both damage and recovery, yet no effective therapy exists to mitigate central nervous system (CNS) injury and promote...
3.
Cai X, Liu C, Tsutsui-Kimura I, Lee J, Guo C, Banerjee A, et al.
Nature
. 2024 Oct;
635(8038):406-414.
PMID: 39415006
Dopamine signalling modes differ in kinetics and spatial patterns of receptor activation. How these modes contribute to motor function, motivation and learning has long been debated. Here we show that...
4.
Lee H, Rone J, Li Z, Faust Akl C, Shin S, Lee J, et al.
Nature
. 2024 Jun;
631(8020):E8.
PMID: 38907058
No abstract available.
5.
Lee H, Rone J, Li Z, Faust Akl C, Shin S, Lee J, et al.
Nature
. 2024 Mar;
627(8005):865-872.
PMID: 38509377
Disease-associated astrocyte subsets contribute to the pathology of neurologic diseases, including multiple sclerosis and experimental autoimmune encephalomyelitis (EAE), an experimental model for multiple sclerosis. However, little is known about the...
6.
Lee H, Rone J, Li Z, Faust Akl C, Shin S, Lee J, et al.
bioRxiv
. 2024 Jan;
PMID: 38260616
Astrocytes play important roles in the central nervous system (CNS) physiology and pathology. Indeed, astrocyte subsets defined by specific transcriptional activation states contribute to the pathology of neurologic diseases, including...
7.
Lee H, Lee J, Flausino L, Quintana F
Sci Transl Med
. 2023 Nov;
15(721):eadi7828.
PMID: 37939162
Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the functional heterogeneity of astrocytes and their...
8.
Lee J, Khan M, Stark A, Seo S, Norton A, Yao Z, et al.
Cell Rep
. 2023 May;
42(5):112429.
PMID: 37141091
Within the cerebellar cortex, mossy fibers (MFs) excite granule cells (GCs) that excite Purkinje cells (PCs), which provide outputs to the deep cerebellar nuclei (DCNs). It is well established that...
9.
Wheeler M, Clark I, Lee H, Li Z, Linnerbauer M, Rone J, et al.
Science
. 2023 Mar;
379(6636):1023-1030.
PMID: 36893254
Cell-cell interactions in the central nervous system play important roles in neurologic diseases. However, little is known about the specific molecular pathways involved, and methods for their systematic identification are...
10.
Shi X, Luo L, Wang J, Shen H, Li Y, Mamtilahun M, et al.
Nat Commun
. 2022 Mar;
13(1):1183.
PMID: 35228547
No abstract available.