Joni Macdonald
Overview
Explore the profile of Joni Macdonald including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
277
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Recent Articles
1.
Wu Z, Shih B, Macdonald J, Meunier D, Hogan K, Chintoan-Uta C, et al.
Front Immunol
. 2023 Nov;
14:1273661.
PMID: 37954617
Conventional dendritic cells (cDCs) are antigen-presenting cells (APCs) that play a central role in linking innate and adaptive immunity. cDCs have been well described in a number of different mammalian...
2.
Pimenta R, Macleod K, Babb R, Coleman K, Macdonald J, Asare-Bediako E, et al.
Plant Dis
. 2023 Oct;
108(3):616-623.
PMID: 37787684
(TuYV; , ) infects and causes yield losses in a range of economically important crop species, particularly the Brassicaceae. It is persistently transmitted by several aphid species and is difficult...
3.
Wu Z, Hu T, Chintoan-Uta C, Macdonald J, Stevens M, Sang H, et al.
Immunology
. 2021 Nov;
165(2):171-194.
PMID: 34767637
Conventional dendritic cells (cDC) are bone marrow-derived immune cells that play a central role in linking innate and adaptive immunity. cDCs efficiently uptake, process and present antigen to naïve T...
4.
Smart E, Macdonald J, Smith L, Mitchell R
Sci Rep
. 2020 Nov;
10(1):19022.
PMID: 33149175
Focal dysgenesis is a consistent feature of testicular dysgenesis syndrome (TDS) in humans. Rodent studies show that perturbation of androgens (e.g. following phthalate exposure) during a fetal masculinisation programming window...
5.
Camacho-Moll M, Macdonald J, Looijenga L, Rimmer M, Donat R, Marwick J, et al.
BMC Cancer
. 2019 Nov;
19(1):1124.
PMID: 31744479
Background: Testicular germ cell cancer (TGCC) develops from pre-malignant germ neoplasia in situ (GCNIS) cells. GCNIS originates from fetal gonocytes (POU5F1/MAGE-A4), which fail to differentiate to pre-spermatogonia (POU5F1/MAGE-A4) and undergo...
6.
Jorgensen A, Macdonald J, Nielsen J, Kilcoyne K, Perlman S, Lundvall L, et al.
Cell Rep
. 2018 Nov;
25(7):1924-1937.e4.
PMID: 30428358
Disruption of human fetal testis development is widely accepted to underlie testicular germ cell cancer (TGCC) origin and additional disorders within testicular dysgenesis syndrome (TDS). However, the mechanisms for the...
7.
Macdonald J, Kilcoyne K, Sharpe R, Kavanagh A, Anderson R, Brown P, et al.
Hum Reprod
. 2018 Oct;
33(11):2107-2121.
PMID: 30272154
Study Question: Does loss of DMRT1 in human fetal testis alter testicular development and result in testicular dysgenesis? Summary Answer: DMRT1 repression in human fetal testis alters the expression of...
8.
Hurtado-Gonzalez P, Anderson R, Macdonald J, van den Driesche S, Kilcoyne K, Jorgensen A, et al.
Environ Health Perspect
. 2018 Apr;
126(4):047006.
PMID: 29665328
Background: Analgesic exposure during pregnancy may affect aspects of fetal gonadal development that are targeted by endocrine disruptors. Objectives: We investigated whether therapeutically relevant doses of acetaminophen and ibuprofen affect...
9.
van den Driesche S, Macdonald J, Anderson R, Johnston Z, Chetty T, Smith L, et al.
Sci Transl Med
. 2015 May;
7(288):288ra80.
PMID: 25995226
Most common male reproductive disorders are linked to lower testosterone exposure in fetal life, although the factors responsible for suppressing fetal testosterone remain largely unknown. Protracted use of acetaminophen during...
10.
Westernstroer B, Langenstroth D, Kliesch S, Troppmann B, Redmann K, Macdonald J, et al.
Cell Tissue Res
. 2015 Mar;
361(3):885-98.
PMID: 25810367
The chemokine receptor CXCR7 interacts with the chemokines CXCL11 and CXCL12. During development, this ligand receptor system (C-X-C) provokes cell-type-specific responses in terms of migration, adhesion or ligand sequestration. It...