Jong-Ding Lay
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Explore the profile of Jong-Ding Lay including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
332
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Recent Articles
1.
Jang T, Lin S, Yang Y, Lay J, Chang C, Yao C, et al.
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001490
Chemotherapy remains a cornerstone in lung cancer treatment, yet emerging evidence suggests that sublethal low doses may inadvertently enhance the malignancy. This study investigates the paradoxical effects of sublethal low-dose...
2.
Yang Y, Lin S, Lay J, Cho C, Jang T, Ku H, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834326
About 80% of lung cancer patients are diagnosed with non-small cell lung cancer (NSCLC). EGFR mutation and overexpression are common in NSCLC, thus making EGFR signaling a key target for...
3.
Cho C, Chung S, Lin S, Huang J, Chen Y, Jiang S, et al.
Sci Rep
. 2019 Nov;
9(1):16922.
PMID: 31729427
AXL is expressed in many types of cancer and promotes cancer cell survival, metastasis and drug resistance. Here, we focus on identifying modulators that regulate AXL at the mRNA level....
4.
Cho C, Huang J, Shiah S, Chung S, Lay J, Yang Y, et al.
RNA
. 2015 Dec;
22(2):303-15.
PMID: 26667302
The AXL receptor tyrosine kinase is frequently overexpressed in cancers and is important in cancer invasion/metastasis and chemoresistance. Here, we demonstrate a regulatory feedback loop between AXL and microRNA (miRNA)...
5.
Huang J, Cho C, Hong C, Yan M, Hsieh M, Lay J, et al.
Free Radic Biol Med
. 2013 Sep;
65:1246-1256.
PMID: 24064382
Persistent oxidative stress is common in cancer cells because of abnormal generation of reactive oxygen species (ROS) and has been associated with malignant phenotypes, such as chemotherapy resistance and metastasis....
6.
Hong C, Lay J, Huang J, Cheng A, Tang J, Lin M, et al.
Cancer Lett
. 2008 May;
268(2):314-24.
PMID: 18502572
By using a novel profiling analysis of protein tyrosine kinases differentially expressed in the sensitive and refractory leukemia from the same patients we found that AXL was upregulated in drug-resistant...
7.
Lu J, Jiang D, Chou S, Hor C, Lay J, Wang H
Kaohsiung J Med Sci
. 2008 Mar;
24(3):144-51.
PMID: 18364275
Although obesity is associated with important hemodynamic disturbances, little data exists on population-wide cardiovascular risk factors in obese adolescent girls in Taiwan. This study measured the prevalence of overweight/obesity and...
8.
Lu J, Lay J
Intervirology
. 2008 Feb;
50(6):454-60.
PMID: 18268409
Aims: To examine the tumor-forming in nude mice of human epithelial cells co-expressed Bcl-2 and EBV LMP-1 ability, the phenotype of tumor cells and their expression of oncogenes and tumor-suppressor...
9.
Chuang H, Lay J, Hsieh W, Su I
Cancer Sci
. 2007 Jul;
98(9):1281-7.
PMID: 17627615
Epstein-Barr virus (EBV) can infect T lymphocytes and manifests as hemophagocytic lymphohistiocytosis (HLH), a distinct entity of hemophagocytic syndrome (HPS) characterized by fever, hepatosplenomegaly, cytopenia, hypercytokinemia, and systemic macrophage activation...
10.
Chuang H, Lay J, Chuang S, Hsieh W, Chang Y, Su I
Am J Pathol
. 2007 Apr;
170(5):1607-17.
PMID: 17456766
The infection of T cells by Epstein-Barr virus (EBV) may result in hemophagocytic syndrome (HPS) through enhanced cytokine secretion, particularly tumor necrosis factor-alpha (TNF-alpha), by EBV latent membrane protein-1 (LMP-1)....