Jonathon E Himes
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Explore the profile of Jonathon E Himes including associated specialties, affiliations and a list of published articles.
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12
Citations
205
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Recent Articles
1.
Su C, Kent C, Pierpoint M, Floyd W, Luo L, Williams N, et al.
JCI Insight
. 2024 Aug;
9(14).
PMID: 39133651
Radiation therapy (RT) is frequently used to treat cancers, including soft-tissue sarcomas. Prior studies established that the toll-like receptor 9 (TLR9) agonist cytosine-phosphate-guanine oligodeoxynucleotide (CpG) enhances the response to RT...
2.
Su C, Himes J, Kirsch D
Int Rev Cell Mol Biol
. 2023 Jul;
378:201-232.
PMID: 37438018
Activating and recruiting the immune system is critical for successful cancer treatment. Since the discovery of immune checkpoint inhibitors, immunotherapy has become the standard of care for many types of...
3.
Himes J, Wisdom A, Wang L, Shepard S, Daniel A, Williams N, et al.
bioRxiv
. 2023 Apr;
PMID: 37066384
The adaptive immune system plays an essential anti-tumor role through immunosurveillance and response to immunotherapies. Characterizing phenotypic features and mechanisms of dysfunction of tumor-specific T cell populations may uncover novel...
4.
Patel R, Mowery Y, Qi Y, Bassil A, Holbrook M, Xu E, et al.
Mol Cancer Ther
. 2022 Sep;
22(1):112-122.
PMID: 36162051
This study aims to investigate whether adding neoadjuvant radiotherapy (RT), anti-programmed cell death protein-1 (PD-1) antibody (anti-PD-1), or RT + anti-PD-1 to surgical resection improves disease-free survival for mice with...
5.
Wisdom A, Mowery Y, Hong C, Himes J, Nabet B, Qin X, et al.
Nat Commun
. 2020 Dec;
11(1):6410.
PMID: 33335088
Immunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induced antitumor immunity. Most preclinical immunotherapy studies utilize transplant tumor models, which overestimate patient...
6.
Wisdom A, Hong C, Lin A, Xiang Y, Cooper D, Zhang J, et al.
Proc Natl Acad Sci U S A
. 2019 Aug;
116(37):18584-18589.
PMID: 31462499
Nearly two-thirds of cancer patients are treated with radiation therapy (RT), often with the intent to achieve complete and permanent tumor regression (local control). RT is the primary treatment modality...
7.
Himes J, Goswami R, Mangan R, Kumar A, Jeffries Jr T, Eudailey J, et al.
Mucosal Immunol
. 2018 Aug;
11(6):1716-1726.
PMID: 30115994
Breast milk HIV-1 transmission is currently the predominant contributor to pediatric HIV infections. Yet, only ~10% of breastfeeding infants born to untreated HIV-infected mothers become infected. This study assessed the...
8.
Nguyen Q, Martinez D, Himes J, Edwards R, Han Q, Kumar A, et al.
Retrovirology
. 2018 Mar;
15(1):24.
PMID: 29523166
Background: The initial envelope (Env)-specific antibody response in acutely HIV-1-infected individuals and simian immunodeficiency virus (SIV)-infected rhesus monkeys (RMs) is dominated by non-neutralizing antibodies targeting Env gp41. In contrast, natural...
9.
Nguyen Q, Himes J, Martinez D, Permar S
PLoS Pathog
. 2016 Dec;
12(12):e1005997.
PMID: 28006021
No abstract available.
10.
Himes J, Ho C, Nguyen Q, Amos J, Xu H, Chan C, et al.
J Virol
. 2016 Jul;
90(19):8795-808.
PMID: 27466415
Unlabelled: Unlike human immunodeficiency virus type 1 (HIV-1)-infected humans, African-origin, natural simian immunodeficiency virus (SIV) hosts, such as African green monkeys (AGMs), sustain nonpathogenic SIV infections and rarely vertically transmit...