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Jonathan Z Long

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Articles 83
Citations 7362
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Recent Articles
1.
Wang Y, Zhang Y, Leung V, Seradj S, Sonmez U, Servin-Vences M, et al.
Cell Metab . 2025 Mar; PMID: 40054462
Compared with the well-established functions of sympathetic innervation, the role of sensory afferents in adipose tissues remains less understood. Recent work has revealed the anatomical and physiological significance of adipose...
2.
Reiss J, Mataraso S, Holzapfel L, Maric I, Kasowski M, Martin C, et al.
Neoreviews . 2025 Jan; 26(2):e100-e114. PMID: 39889768
The metabolome and lipidome comprise the thousands of molecular compounds in an organism. Molecular compounds consist of the upstream metabolic components of intracellular reactions or the byproducts of cellular pathways....
3.
Reiss J, Yang W, Chang A, Long J, Maric I, Profit J, et al.
Sci Rep . 2025 Jan; 15(1):1144. PMID: 39774255
Maternal obesity increases risk for bronchopulmonary dysplasia (BPD) by up to 42%. Identifying metabolic features that may contribute to the association between maternal pre-pregnancy body mass index (BMI) and BPD...
4.
Moya-Garzon M, Wang M, Li V, Lyu X, Wei W, Tung A, et al.
Cell . 2024 Nov; 188(1):175-186.e20. PMID: 39536746
β-Hydroxybutyrate (BHB) is an abundant ketone body. To date, all known pathways of BHB metabolism involve the interconversion of BHB and primary energy intermediates. Here, we identify a previously undescribed...
5.
Moya-Garzon M, Wang M, Li V, Lyu X, Wei W, Tung A, et al.
bioRxiv . 2024 Sep; PMID: 39314488
β-hydroxybutyrate (BHB) is an abundant ketone body. To date, all known pathways of BHB metabolism involve interconversion of BHB and primary energy intermediates. Here we show that CNDP2 controls a...
6.
Mehdipour M, Park S, Wei W, Long J, Huang G
bioRxiv . 2024 Aug; PMID: 39211274
Cardiac aging involves the development of left ventricular hypertrophy alongside a decline in functional capacity. Here, we use neutral blood exchange to demonstrate that the acute removal of age-accumulated blood...
7.
Xiao S, Li V, Long J
Trends Endocrinol Metab . 2024 Aug; 35(8):758-759. PMID: 39137723
No abstract available.
8.
Li V, Xiao S, Schlosser P, Scherer N, Wiggenhorn A, Spaas J, et al.
Nat Commun . 2024 Aug; 15(1):6895. PMID: 39134528
N-lactoyl-phenylalanine (Lac-Phe) is a lactate-derived metabolite that suppresses food intake and body weight. Little is known about the mechanisms that mediate Lac-Phe transport across cell membranes. Here we identify SLC17A1...
9.
Wei W, Lyu X, Markhard A, Fu S, Mardjuki R, Cavanagh P, et al.
Nature . 2024 Aug; 633(8028):182-188. PMID: 39112712
Taurine is a conditionally essential micronutrient and one of the most abundant amino acids in humans. In endogenous taurine metabolism, dedicated enzymes are involved in the biosynthesis of taurine from...
10.
Durrer C, Islam H, Cen H, Garzon M, Lyu X, McKelvey S, et al.
Nutr Metab (Lond) . 2024 May; 21(1):29. PMID: 38797835
Background: Substantial weight loss in people living with type 2 diabetes (T2D) can reduce the need for glucose-lowering medications while concurrently lowering glycemia below the diagnostic threshold for the disease....