Jonathan S Minden
Overview
Explore the profile of Jonathan S Minden including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
368
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Recent Articles
1.
Biedka S, Yablonska S, Peng X, Alkam D, Hartoyo M, VanEvery H, et al.
J Proteome Res
. 2025 Jan;
24(2):795-812.
PMID: 39814365
Immunoprecipitation is among the most widely utilized methods in biomedical research, with applications that include the identification of antibody targets and associated proteins. The path to identifying these targets is...
2.
Sonmez U, Frey N, LeDuc P, Minden J
Annu Rev Biomed Eng
. 2024 Jul;
26(1):441-473.
PMID: 38959386
Multicellular model organisms, such as (fruit fly), are frequently used in a myriad of biological research studies due to their biological significance and global standardization. However, traditional tools used in...
3.
Biedka S, Alkam D, Washam C, Yablonska S, Storey A, Byrum S, et al.
Commun Biol
. 2024 Mar;
7(1):324.
PMID: 38485785
Typical multiomics studies employ separate methods for DNA, RNA, and protein sample preparation, which is labor intensive, costly, and prone to sampling bias. We describe a method for preparing high-quality,...
4.
Sonmez U, Frey N, Minden J, LeDuc P
J Vis Exp
. 2023 Jan;
(190).
PMID: 36622011
During embryogenesis, coordinated cell movement generates mechanical forces that regulate gene expression and activity. To study this process, tools such as aspiration or coverslip compression have been used to mechanically...
5.
Warecki B, Titen S, Alam M, Vega G, Lemseffer N, Hug K, et al.
Elife
. 2022 Sep;
11.
PMID: 36149408
, a vertically transmitted endosymbiont infecting many insects, spreads rapidly through uninfected populations by a mechanism known as cytoplasmic incompatibility (CI). In CI, a paternally delivered modification of the sperm...
6.
Jacqueline C, Dracz M, Boothman S, Minden J, Gottschalk R, Finn O
Front Immunol
. 2021 Oct;
12:749597.
PMID: 34712237
The ability of immune cells to sense changes associated with malignant transformation as early as possible is likely to be important for the successful outcome of cancer immunosurveillance. In this...
7.
Biedka S, Schmidt B, Frey N, Boothman S, Minden J, Wilson A
J Proteome Res
. 2021 Sep;
20(10):4787-4800.
PMID: 34524823
Successful proteome analysis requires reliable sample preparation beginning with protein solubilization and ending with a sample free of contaminants, ready for downstream analysis. Most proteome sample preparation technologies utilize precipitation...
8.
Jacqueline C, Lee A, Frey N, Minden J, Finn O
Cancer Immunol Res
. 2020 May;
8(8):1027-1038.
PMID: 32467324
Tumor-associated antigens (TAA) are self-molecules abnormally expressed on tumor cells, which elicit humoral and cellular immunity and are targets of immunosurveillance. Immunity to TAAs is found in some healthy individuals...
9.
Yablonska S, Ganesan V, Ferrando L, Kim J, Pyzel A, Baranova O, et al.
Proc Natl Acad Sci U S A
. 2019 Jul;
116(33):16593-16602.
PMID: 31346086
Mutant huntingtin (mHTT), the causative protein in Huntington's disease (HD), associates with the translocase of mitochondrial inner membrane 23 (TIM23) complex, resulting in inhibition of synaptic mitochondrial protein import first...
10.
Shorr A, Sonmez U, Minden J, LeDuc P
Lab Chip
. 2019 Feb;
19(7):1141-1152.
PMID: 30778467
Developing embryos create complexity by expressing genes to coordinate movement which generates mechanical force. An emerging theory is that mechanical force can also serve as an input signal to regulate...