Jonathan R Beauchamp
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Explore the profile of Jonathan R Beauchamp including associated specialties, affiliations and a list of published articles.
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13
Citations
1077
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Recent Articles
1.
Low S, Barnes J, Zammit P, Beauchamp J
Stem Cells
. 2017 Dec;
36(3):458-466.
PMID: 29230914
Notch signaling is essential to maintain skeletal muscle stem cells in quiescence. However, the precise roles of different Notch receptors are incompletely defined. Here, we demonstrate a role for Notch3...
2.
Golding J, Calderbank E, Partridge T, Beauchamp J
Exp Cell Res
. 2006 Nov;
313(2):341-56.
PMID: 17123512
To be effective for tissue repair, satellite cells (the stem cells of adult muscle) must survive the initial activation from quiescence. Using an in vitro model of satellite cell activation,...
3.
Zammit P, Relaix F, Nagata Y, Perez Ruiz A, Collins C, Partridge T, et al.
J Cell Sci
. 2006 Apr;
119(Pt 9):1824-32.
PMID: 16608873
Skeletal muscle growth and regeneration are attributed to satellite cells - muscle stem cells resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells express the transcription factor...
4.
Golding J, Tsoni S, Dixon M, Yee K, Partridge T, Beauchamp J, et al.
Gene Expr Patterns
. 2004 Nov;
5(1):3-9.
PMID: 15533812
Heparin-binding EGF-like growth factor (HB-EGF) is a potent mitogen and chemoattractant for diverse cell types including, keratinocytes, fibroblasts and vascular smooth muscle cells. In adult mice, skeletal muscle and endothelial...
5.
Golding J, Partridge T, Beauchamp J, King T, Brown N, Gassmann M, et al.
Dev Dyn
. 2004 Oct;
231(4):795-800.
PMID: 15499557
Most muscle originates from the myotomal compartment of the somites, paired structures flanking the neural tube. Whereas vertebrate embryos show molecular and morphological asymmetry about the left-right body axis, somitic...
6.
Suzuki K, Murtuza B, Beauchamp J, Brand N, Barton P, Varela-Carver A, et al.
Circulation
. 2004 Sep;
110(11 Suppl 1):II219-24.
PMID: 15364866
Background: Poor survival of grafted cells is a major factor hindering the therapeutic effect of cell transplantation; however, the causes of cell death remain unclear. We hypothesized that interleukin-1beta (IL-1beta)...
7.
Zammit P, Carvajal J, Golding J, Morgan J, Summerbell D, Zolnerciks J, et al.
Dev Biol
. 2004 Aug;
273(2):454-65.
PMID: 15328025
The myogenic regulatory factor Myf5 is integral to the initiation and control of skeletal muscle formation. In adult muscle, Myf5 is expressed in satellite cells, stem cells of mature muscle,...
8.
Zammit P, Golding J, Nagata Y, Hudon V, Partridge T, Beauchamp J
J Cell Biol
. 2004 Jul;
166(3):347-57.
PMID: 15277541
Growth, repair, and regeneration of adult skeletal muscle depends on the persistence of satellite cells: muscle stem cells resident beneath the basal lamina that surrounds each myofiber. However, how the...
9.
Suzuki K, Murtuza B, Beauchamp J, Smolenski R, Varela-Carver A, Fukushima S, et al.
FASEB J
. 2004 May;
18(10):1153-5.
PMID: 15155562
Survival and proliferation of skeletal myoblasts within the cardiac environment are crucial to the therapeutic efficacy of myoblast transplantation to the heart. We have analyzed the early dynamics of myoblasts...
10.
Murtuza B, Suzuki K, Bou-Gharios G, Beauchamp J, Smolenski R, Partridge T, et al.
Proc Natl Acad Sci U S A
. 2004 Mar;
101(12):4216-21.
PMID: 15020774
After myocardial infarction (MI), adverse remodeling with left ventricular (LV) dilatation is a major determinant of poor outcome. Skeletal myoblast (SkM) implantation improves cardiac function post-MI, although the mechanism is...