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Jonathan Perreault

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Articles 37
Citations 497
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Recent Articles
1.
Chenal M, Rivera-Millot A, Harrison L, Khairalla A, Nieves C, Bernet E, et al.
Nat Commun . 2025 Mar; 16(1):2388. PMID: 40064889
Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies. We identify and characterize one such family, from...
2.
Kapadia J, Daoud J, Perreault J
Analyst . 2025 Feb; PMID: 39903496
Toehold mediated strand displacement reaction (TMSDR) offers a rapid, enzyme-free amplification strategy, providing advantages over traditional methods like RT-PCR, and RT-LAMP. Optimizing TMSDR can significantly enhance sensitivity in point-of-care biosensor...
3.
Yurdusev E, Trahan P, Perreault J
Sensors (Basel) . 2024 Nov; 24(21). PMID: 39517771
Isothermal amplification (IA) techniques like rolling circle amplification (RCA) and loop-mediated isothermal amplification (LAMP) have gained significant attention in recent years due to their ability to rapidly amplify DNA or...
4.
Lecuyer E, Sauvageau M, Kothe U, Unrau P, Damha M, Perreault J, et al.
Biochem Cell Biol . 2024 Sep; 102(6):472-491. PMID: 39320985
The field of RNA research has provided profound insights into the basic mechanisms modulating the function and adaption of biological systems. RNA has also been at the center stage in...
5.
Lei Y, Ossonon B, Trahan P, Chen J, Perreault J, Tavares A
ACS Appl Mater Interfaces . 2023 Jul; 15(29):35580-35589. PMID: 37439592
Transducers made from graphene-type materials are widely used in sensing applications. However, utilization of graphene oxide obtained from electrochemical exfoliation of graphite (EGO) has remained relatively unexplored. In this study,...
6.
Najeh S, Zandi K, Kharma N, Perreault J
RNA . 2023 Mar; 29(6):764-776. PMID: 36868786
The design of new RNA sequences that retain the function of a model RNA structure is a challenge in bioinformatics because of the structural complexity of these molecules. RNA can...
7.
Boutet E, Djerroud S, Perreault J
Int J Mol Sci . 2022 Apr; 23(8). PMID: 35457265
Small RNAs (sRNAs) are essential regulators in the adaptation of bacteria to environmental changes and act by binding targeted mRNAs through base complementarity. Approximately 550 distinct families of sRNAs have...
8.
Korniakova V, Devinck A, Groleau M, Deziel E, Perreault J
Front Genet . 2022 Feb; 12:591543. PMID: 35126444
Bioreporter systems based on detectable enzyme activity, such as that of beta-galactosidase or luciferase, are key in novel bacterial promoter discovery and study. While these systems permit quantification of gene...
9.
Kapadia J, Kharma N, Davis A, Kamel N, Perreault J
RNA . 2021 Dec; 28(2):263-273. PMID: 34862273
This paper presents a probe comprising a fluorophore and a quencher, enabling measurement of released product from self-cleaving hammerhead ribozyme, without labeled RNA molecules, regular sampling or use of polyacrylamide...
10.
Mohamed A, Walsh R, Cherif M, Hafez H, Ropagnol X, Vidal F, et al.
Analyst . 2021 Nov; 146(24):7583-7592. PMID: 34780591
We demonstrate the rapid and highly sensitive detection of a small molecule, microcystin-LR (MC-LR) toxin using an aptasensor based on a terahertz (THz) emission technique named the terahertz chemical microscope...