Jonathan M Philpott
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Explore the profile of Jonathan M Philpott including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
250
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Recent Articles
1.
Serra F, Philpott J, Bulysheva A, Zemlin C
JTCVS Open
. 2025 Mar;
23:128-133.
PMID: 40061523
Objective: Atrial cryolesions usually are created from the endocardium with the heart arrested. Some cardiac surgeons have used cryoablation epicardially during cardiopulmonary bypass, which is convenient because it does not...
2.
Ricci C, Philpott J, Torgrimson M, Freeberg A, Narasimamurthy R, de Barros E, et al.
bioRxiv
. 2025 Feb;
PMID: 39896482
Circadian rhythms in mammals are tightly regulated through phosphorylation of Period (PER) proteins by Casein Kinase 1 (CK1, subtypes δ and ε). CK1 acts on at least two different regions...
3.
Serra F, Philpott J, Neuber J, Shih E, Etheridge J, Varghese F, et al.
Circ Arrhythm Electrophysiol
. 2023 Nov;
16(11):e012300.
PMID: 37920983
No abstract available.
4.
Philpott J, Freeberg A, Park J, Lee K, Ricci C, Hunt S, et al.
Mol Cell
. 2023 May;
83(10):1677-1692.e8.
PMID: 37207626
PERIOD (PER) and Casein Kinase 1δ regulate circadian rhythms through a phosphoswitch that controls PER stability and repressive activity in the molecular clock. CK1δ phosphorylation of the familial advanced sleep...
5.
Varghese F, Philpott J, Neuber J, Hargrave B, Zemlin C
Cardiovasc Eng Technol
. 2022 Jun;
14(1):52-59.
PMID: 35705890
Background: Myocardial tissue can be ablated by the application nanosecond pulsed fields (nsPEFs). The applied electric fields irreversibly permeabilize cell membranes and thereby kill myocytes while leaving the extracellular matrix...
6.
Philpott J, Torgrimson M, Harold R, Partch C
Semin Cell Dev Biol
. 2021 May;
126:71-78.
PMID: 33933351
Genetically encoded biological clocks are found broadly throughout life on Earth, where they generate circadian (about a day) rhythms that synchronize physiology and behavior with the daily light/dark cycle. Although...
7.
Etheridge J, Cousins R, Philpott J
J Card Surg
. 2020 Oct;
36(1):381-383.
PMID: 33111997
Left ventricular assist devices (LVADs) have become integral to the treatment of advanced heart failure. Surgical bleeding is a known complication of LVAD placement but is most associated with intraperitoneal...
8.
Philpott J, Narasimamurthy R, Ricci C, Freeberg A, Hunt S, Yee L, et al.
Elife
. 2020 Feb;
9.
PMID: 32043967
Post-translational control of PERIOD stability by Casein Kinase 1δ and ε (CK1) plays a key regulatory role in metazoan circadian rhythms. Despite the deep evolutionary conservation of CK1 in eukaryotes,...
9.
Varghese F, Neuber J, Xie F, Philpott J, Pakhomov A, Zemlin C
Cardiovasc Res
. 2017 Oct;
113(14):1789-1797.
PMID: 29016714
Aims: Reliable defibrillation with reduced energy deposition has long been the focus of defibrillation research. We studied the efficacy of single shocks of 300 ns duration in defibrillating rabbit hearts...
10.
Badhwar V, Rankin J, Damiano Jr R, Gillinov A, Bakaeen F, Edgerton J, et al.
Ann Thorac Surg
. 2016 Dec;
103(1):329-341.
PMID: 28007240
Surgical ablation for atrial fibrillation (AF) can be performed without additional risk of operative mortality or major morbidity, and is recommended at the time of concomitant mitral operations to restore...