Jonathan L Dean
Overview
Explore the profile of Jonathan L Dean including associated specialties, affiliations and a list of published articles.
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4
Citations
131
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Recent Articles
1.
ONeil J, Ross E, Ridley M, Ding Q, Tang T, Rosner D, et al.
Mol Cell Biol
. 2017 Mar;
37(11).
PMID: 28265004
The mRNA-destabilizing factor tristetraprolin (TTP) binds in a sequence-specific manner to the 3' untranslated regions of many proinflammatory mRNAs and recruits complexes of nucleases to promote rapid mRNA turnover. Mice...
2.
Smallie T, Ross E, Ammit A, Cunliffe H, Tang T, Rosner D, et al.
J Immunol
. 2015 May;
195(1):277-88.
PMID: 26019272
Dual-specificity phosphatase (DUSP) 1 dephosphorylates and inactivates members of the MAPK superfamily, in particular, JNKs, p38α, and p38β MAPKs. It functions as an essential negative regulator of innate immune responses,...
3.
Ross E, Smallie T, Ding Q, ONeil J, Cunliffe H, Tang T, et al.
J Immunol
. 2015 May;
195(1):265-76.
PMID: 26002976
In myeloid cells, the mRNA-destabilizing protein tristetraprolin (TTP) is induced and extensively phosphorylated in response to LPS. To investigate the role of two specific phosphorylations, at serines 52 and 178,...
4.
Iqbal M, Johns M, Cao J, Liu Y, Yu S, Hyde G, et al.
Blood
. 2014 Oct;
124(24):3646-55.
PMID: 25293769
Tissue factor (TF) (CD142) is a 47 kDa transmembrane cell surface glycoprotein that triggers the extrinsic coagulation cascade and links thrombosis with inflammation. Although macrophage TF expression is known to...