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Jonathan J Chow

Explore the profile of Jonathan J Chow including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 262
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Recent Articles
1.
Chow J, Madangopal R, Shaham Y
Neuron . 2024 Aug; 112(16):2666-2668. PMID: 39173589
In this issue of Neuron, Chen et al. found that lateral septum Esr1-expressing cells respond to both non-drug and drug rewards. Mice will lever press for optogenetic stimulation of these...
2.
Chow J, Pitts K, Chabot J, Ito R, Shaham Y
Psychopharmacology (Berl) . 2024 Apr; 241(9):1791-1813. PMID: 38642101
Rationale And Objective: Avoidance of opioid withdrawal plays a key role in human opioid addiction. Here, we present a procedure for studying operant negative reinforcement in rats that was inspired...
3.
Chow J, Pitts K, Schoenbaum A, Costa K, Schoenbaum G, Shaham Y
J Neurosci . 2024 Feb; 44(10). PMID: 38346894
When rats are given discrete choices between social interactions with a peer and opioid or psychostimulant drugs, they choose social interaction, even after extensive drug self-administration experience. Studies show that...
4.
Claypool S, Reiner D, Behdin S, Orihuel J, Batista A, Caldwell K, et al.
J Neurosci . 2023 Mar; 43(14):2597-2614. PMID: 36898838
We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after food choice-induced voluntary abstinence. Here, we used this model to further study the role of...
5.
Bossert J, Mejias-Aponte C, Saunders T, Altidor L, Emery M, Fredriksson I, et al.
J Neurosci . 2023 Jan; 43(10):1692-1713. PMID: 36717230
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells...
6.
Fredriksson I, Tsai P, Shekara A, Duan Y, Applebey S, Minier-Toribio A, et al.
Sci Adv . 2023 Jan; 9(2):eadd8687. PMID: 36630511
High relapse rate is a key feature of opioid addiction. In humans, abstinence is often voluntary due to negative consequences of opioid seeking. To mimic this human condition, we recently...
7.
Venniro M, Marino R, Chow J, Caprioli D, Epstein D, Ramsey L, et al.
J Neurosci . 2022 Dec; 42(50):9298-9314. PMID: 36517252
Until recently, most modern neuroscience research on addiction using animal models did not incorporate manipulations of social factors. Social factors play a critical role in human addiction: social isolation and...
8.
Chow J, Beacher N, Chabot J, Oke M, Venniro M, Lin D, et al.
Psychopharmacology (Berl) . 2022 Mar; 239(7):2093-2108. PMID: 35230469
Rationale And Objective: Social factors play a critical role in drug addiction. We recently showed that rats will abstain from methamphetamine, cocaine, heroin, and remifentanil self-administration when given a choice...
9.
Fredriksson I, Venniro M, Reiner D, Chow J, Bossert J, Shaham Y
Pharmacol Rev . 2021 Jul; 73(3):1050-1083. PMID: 34257149
Relapse to drug use during abstinence is a defining feature of addiction. During the last several decades, this clinical scenario has been studied at the preclinical level using classic relapse/reinstatement...
10.