Jonathan Hetzel
Overview
Explore the profile of Jonathan Hetzel including associated specialties, affiliations and a list of published articles.
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10
Citations
1553
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Recent Articles
1.
Crits-Christoph A, Kantor R, Olm M, Whitney O, Al-Shayeb B, Lou Y, et al.
mBio
. 2021 Jan;
12(1).
PMID: 33468686
Viral genome sequencing has guided our understanding of the spread and extent of genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. SARS-CoV-2 viral genomes are usually sequenced from nasopharyngeal swabs...
2.
Colman R, Mace A, Seifert M, Hetzel J, Mshaiel H, Suresh A, et al.
PLoS Med
. 2019 May;
16(4):e1002794.
PMID: 31039166
Background: Accurate, comprehensive, and timely detection of drug-resistant tuberculosis (TB) is essential to inform patient treatment and enable public health surveillance. This is crucial for effective control of TB globally....
3.
Liu W, Duttke S, Hetzel J, Groth M, Feng S, Gallego-Bartolome J, et al.
Nat Plants
. 2018 Jan;
4(3):181-188.
PMID: 29379150
Small RNAs regulate chromatin modifications such as DNA methylation and gene silencing across eukaryotic genomes. In plants, RNA-directed DNA methylation (RdDM) requires 24-nucleotide small interfering RNAs (siRNAs) that bind to...
4.
Hetzel J, Duttke S, Benner C, Chory J
Proc Natl Acad Sci U S A
. 2016 Oct;
113(43):12316-12321.
PMID: 27729530
Transcriptional regulation of gene expression is a major mechanism used by plants to confer phenotypic plasticity, and yet compared with other eukaryotes or bacteria, little is known about the design...
5.
Pedmale U, Huang S, Zander M, Cole B, Hetzel J, Ljung K, et al.
Cell
. 2016 Jan;
164(1-2):233-245.
PMID: 26724867
Sun-loving plants have the ability to detect and avoid shading through sensing of both blue and red light wavelengths. Higher plant cryptochromes (CRYs) control how plants modulate growth in response...
6.
Zhong X, Hale C, Nguyen M, Ausin I, Groth M, Hetzel J, et al.
Proc Natl Acad Sci U S A
. 2015 Jan;
112(3):911-6.
PMID: 25561521
DNA methylation is a mechanism of epigenetic gene regulation and genome defense conserved in many eukaryotic organisms. In Arabidopsis, the DNA methyltransferase domains rearranged methylase 2 (DRM2) controls RNA-directed DNA...
7.
Belkhadir Y, Yang L, Hetzel J, Dangl J, Chory J
Trends Biochem Sci
. 2014 Aug;
39(10):447-56.
PMID: 25089011
Plants must adapt to their environment and require mechanisms for sensing their surroundings and responding appropriately. An expanded family of more than 200 leucine-rich repeat (LRR) receptor kinases (LRR-RKs) transduces...
8.
Du J, Zhong X, Bernatavichute Y, Stroud H, Feng S, Caro E, et al.
Cell
. 2012 Oct;
151(1):167-80.
PMID: 23021223
DNA methylation and histone modification exert epigenetic control over gene expression. CHG methylation by CHROMOMETHYLASE3 (CMT3) depends on histone H3K9 dimethylation (H3K9me2), but the mechanism underlying this relationship is poorly...
9.
Wilkes D, Bennardo N, Chan C, Chang Y, Corpuz E, Dumond J, et al.
Methods Cell Biol
. 2010 Apr;
92:11-30.
PMID: 20409796
We describe the protocol through which we identify and characterize dynein subunit genes in the ciliated protozoan Tetrahymena thermophila. The gene(s) of interest is found by searching the Tetrahymena genome,...
10.
Feng S, Cokus S, Zhang X, Chen P, Bostick M, Goll M, et al.
Proc Natl Acad Sci U S A
. 2010 Apr;
107(19):8689-94.
PMID: 20395551
Cytosine DNA methylation is a heritable epigenetic mark present in many eukaryotic organisms. Although DNA methylation likely has a conserved role in gene silencing, the levels and patterns of DNA...