Jonathan E Wilson
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Explore the profile of Jonathan E Wilson including associated specialties, affiliations and a list of published articles.
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15
Citations
164
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Recent Articles
1.
Simonds E, Gobenciong K, Wilson J, Jiroutek M, Nugent N, van Tilburg M
Children (Basel)
. 2022 Jul;
9(7).
PMID: 35883935
Background: There is worldwide consensus that providing secondary prevention to promote resilience and prevent mental health concerns after a disaster is important. However, data supporting this kind of intervention is...
2.
Bommi-Reddy A, Park-Chouinard S, Mayhew D, Terzo E, Hingway A, Steinbaugh M, et al.
PLoS One
. 2022 Mar;
17(3):e0262378.
PMID: 35353838
Therapeutic targeting of the estrogen receptor (ER) is a clinically validated approach for estrogen receptor positive breast cancer (ER+ BC), but sustained response is limited by acquired resistance. Targeting the...
3.
Morriello G, Dwyer M, Chen Y, Ginetti A, Xu S, Lu J, et al.
Bioorg Med Chem Lett
. 2021 May;
44:128082.
PMID: 33991626
A focused SAR study was conducted on a series of N1-substituted pyrazolopyrimidinone PDE2 inhibitors to reveal compounds with excellent potency and selectivity. The series was derived from previously identified internal...
4.
Wilson J, Patel G, Patel C, Brucelle F, Huhn A, Gardberg A, et al.
ACS Med Chem Lett
. 2020 Jun;
11(6):1324-1329.
PMID: 32551019
The histone acetyltransferases, CREB binding protein (CBP) and EP300, are master transcriptional co-regulators that have been implicated in numerous diseases, such as cancer, inflammatory disorders, and neurodegeneration. A novel, highly...
5.
Huhn A, Gardberg A, Poy F, Brucelle F, Vivat V, Cantone N, et al.
ChemMedChem
. 2020 Mar;
15(11):955-960.
PMID: 32181984
EP300 and CBP (KAT3A/3B) are two highly homologous, multidomain, epigenetic coregulators that play central roles in transcription through the acetylation of lysine residues on histones and other proteins. Both enzymes...
6.
Wilson J, Kurukulasuriya R, Sinz C, Lombardo M, Bender K, Parker D, et al.
Bioorg Med Chem Lett
. 2016 Jun;
26(12):2947-2951.
PMID: 27240550
A novel series of benzo-[1,2,4]-triazolo-[1,4]-oxazepine GPR142 agonists are described. The series was designed to address the suboptimal PK (pharmacokinetic) and off-target profile of a class of N-aryl-benzo-[1,4]-oxazepine-4-carboxamides, represented by 1,...
7.
Wilson J, Kurukulasuriya R, Reibarkh M, Reiter M, Zwicker A, Zhao K, et al.
ACS Med Chem Lett
. 2016 Mar;
7(3):261-5.
PMID: 26985312
Using the collective body of known (CETP) inhibitors as inspiration for design, a structurally novel series of tetrahydroquinoxaline CETP inhibitors were discovered. An exemplar from this series, compound 5, displayed...
8.
Wilson J, Galinanes E, Hu P, Dombrovskiy V, Vogel T
Vascular
. 2013 Sep;
22(4):239-45.
PMID: 24003009
Objective: We aimed to evaluate outcomes of thoracic endovascular aortic repair (TEVAR) with left subclavian artery (LSA) coverage without bypass (TEVAR + SUB) to TEVAR with coverage of the LSA...
9.
Patterson J, Wilson J, Dim D, Talboy G
Breast Dis
. 2013 Mar;
33(4):189-91.
PMID: 23532152
Sarcomas of the breast are rare, comprising 1% of all breast tumors. Primary chondrosarcomas of the breast account for an extremely rare subset of such tumors, with few reports in...
10.
Strotman N, Chobanian H, Guo Y, He J, Wilson J
Org Lett
. 2010 Aug;
12(16):3578-81.
PMID: 20704397
Complementary palladium-catalyzed methods for direct arylation of oxazole with high regioselectivity (>100:1) at both C-5 and C-2 have been developed for a wide range of aryl and heteroaryl bromides, chlorides,...