Jonathan E Barnes
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Explore the profile of Jonathan E Barnes including associated specialties, affiliations and a list of published articles.
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11
Citations
34
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Recent Articles
1.
Fogg L, Isari S, Barnes J, Patel J, Marshall N, Salzburger W, et al.
bioRxiv
. 2024 Oct;
PMID: 39416096
Vertebrate vision is accomplished by two phenotypically distinct types of photoreceptors in the retina: the saturation-resistant cones for the detection of bright light and the highly sensitive rods for dim...
2.
Barnes J, America Chi L, Ytreberg F, Patel J
bioRxiv
. 2024 Oct;
PMID: 39386633
Proteins play a pivotal role in many biological processes, and changes in their amino acid sequences can lead to dysfunction and disease. These changes can affect protein folding or interaction...
3.
America Chi L, Pandey S, Kolodziejczyk W, Lund-Andersen P, Barnes J, Kapusta K, et al.
bioRxiv
. 2024 Oct;
PMID: 39386526
Visual pigments are essential for converting light into electrical signals during vision. Composed of an opsin protein and a retinal-based chromophore, pigments in vertebrate rods (Rh1) and cones (Rh2) have...
4.
America Chi L, Barnes J, Patel J, Ytreberg F
Sci Rep
. 2024 Oct;
14(1):23122.
PMID: 39366988
Antibody escape mutations pose a significant challenge to the effectiveness of vaccines and antibody-based therapies. The ability to predict these escape mutations with computer simulations would allow us to detect...
5.
America Chi L, Barnes J, Patel J, Ytreberg F
bioRxiv
. 2024 Jun;
PMID: 38826284
Antibody escape mutations pose a significant challenge to the effectiveness of vaccines and antibody-based therapies. The ability to predict these escape mutations with computer simulations would allow us to detect...
6.
Taggart N, Crabtree A, Creagh J, Bizarria Jr R, Li S, de la Higuera I, et al.
PLoS Pathog
. 2023 Jun;
19(6):e1011418.
PMID: 37285383
It has been 49 years since the last discovery of a new virus family in the model yeast Saccharomyces cerevisiae. A large-scale screen to determine the diversity of double-stranded RNA...
7.
Barnes J, Lund-Andersen P, Patel J, Ytreberg F
Sci Rep
. 2022 Nov;
12(1):18819.
PMID: 36335244
SARS-CoV-2 is the pathogen responsible for COVID-19 that has claimed over six million lives as of July 2022. The severity of COVID-19 motivates a need to understand how it could...
8.
Eilertsen M, Davies W, Patel D, Barnes J, Karlsen R, Mountford J, et al.
Front Neuroanat
. 2022 Jul;
16:945344.
PMID: 35899127
Salmonids are ideal models as many species follow a distinct developmental program from demersal eggs and a large yolk sac to hatching at an advanced developmental stage. Further, these economically...
9.
Barnes J, Miller C, Ytreberg F
Proteins
. 2022 Feb;
90(7):1474-1485.
PMID: 35218569
When two or more amino acid mutations occur in protein systems, they can interact in a nonadditive fashion termed epistasis. One way to quantify epistasis between mutation pairs in protein...
10.
Gonzalez T, Martin K, Barnes J, Patel J, Ytreberg F
PLoS One
. 2020 Dec;
15(12):e0240573.
PMID: 33347442
A growing number of computational tools have been developed to accurately and rapidly predict the impact of amino acid mutations on protein-protein relative binding affinities. Such tools have many applications,...