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Jonathan E Bard

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Articles 30
Citations 551
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Recent Articles
1.
Bard J, Jiang N, Emerson J, Bartz M, Lamb N, Marzullo B, et al.
Front Microbiol . 2024 Oct; 15:1416580. PMID: 39397798
The COVID-19 pandemic has prompted an unprecedented global effort to understand and mitigate the spread of the SARS-CoV-2 virus. In this study, we present a comprehensive analysis of COVID-19 in...
2.
Bard J, Tylec B, Dubey A, Lamb N, Yergeau D, Read L
Proc Natl Acad Sci U S A . 2024 Jul; 121(29):e2403188121. PMID: 38990950
The kinetoplastid parasite, , undergoes a complex life cycle entailing slender and stumpy bloodstream forms in mammals and procyclic and metacyclic forms (MFs) in tsetse fly hosts. The numerous gene...
3.
Campbell C, Webber K, Bard J, Chaves L, Osinski J, Gronostajski R
Stem Cells Dev . 2024 Feb; 33(7-8):153-167. PMID: 38366751
Mouse postnatal neural stem cells (pNSCs) can be expanded in vitro in the presence of epidermal growth factor and fibroblast growth factor 2 and upon removal of these factors cease...
4.
Mathuram T, Su Y, Bard J, Perry N, Chen C, Warren M, et al.
bioRxiv . 2024 Jan; PMID: 38293158
Rationale: We showed that levels of a murine mitochondrial noncoding RNA, , increase in alveolar epithelial type 2 cells exposed to extracts from cigarette smoke. The transcripts translocate to the...
5.
Zhang L, Kwack K, Thiyagarajan R, Mullaney K, Lamb N, Bard J, et al.
FASEB J . 2023 Dec; 38(1):e23338. PMID: 38038723
Tristetraprolin (TTP; also known as NUP475, GOS24, or TIS11), encoded by Zfp36, is an RNA-binding protein that regulates target gene expression by promoting mRNA decay and preventing translation. Although previous...
6.
Segelhurst E, Bard J, Pillsbury A, Alam M, Lamb N, Zhu C, et al.
ACS ES T Water . 2023 Jul; 3(4):954-962. PMID: 37406038
The sequencing of human virus genomes from wastewater samples is an efficient method for tracking viral transmission and evolution at the community level. However, this requires the recovery of viral...
7.
Patel A, Pietromicca J, Venkatesan M, Maity S, Bard J, Madesh M, et al.
Physiol Rep . 2023 Feb; 11(3):e15588. PMID: 36754446
Mitochondrial calcium ( Ca ) uptake occurs via the Mitochondrial Ca Uniporter (MCU) complex and plays a critical role in mitochondrial dynamics, mitophagy, and apoptosis. MCU complex activity is in...
8.
Kwack K, Zhang L, Kramer E, Thiyagarajan R, Lamb N, Arao Y, et al.
Front Immunol . 2022 Oct; 13:1002163. PMID: 36263047
Aging results in enhanced myelopoiesis, which is associated with an increased prevalence of myeloid leukemias and the production of myeloid-derived suppressor cells (MDSCs). Tristetraprolin (TTP) is an RNA binding protein...
9.
Bard J, Nowak N, Buck M, Sinha S
Front Oncol . 2022 Aug; 12:892207. PMID: 35912202
Traditional analysis of genomic data from bulk sequencing experiments seek to group and compare sample cohorts into biologically meaningful groups. To accomplish this task, large scale databases of patient-derived samples,...
10.
Lamb N, Bard J, Loll-Krippleber R, Brown G, Surtees J
Genetics . 2022 Jun; 221(4). PMID: 35686905
Determining mutation signatures is standard for understanding the etiology of human tumors and informing cancer treatment. Multiple determinants of DNA replication fidelity prevent mutagenesis that leads to carcinogenesis, including the...